Osborne BA - Search Results

1

Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. Golde TE, et al. Among authors: osborne ba. Biochim Biophys Acta. 2013 Dec;1828(12):2898-907. doi: 10.1016/j.bbamem.2013.06.005. Epub 2013 Jun 17. Biochim Biophys Acta. 2013. PMID: 23791707 Free PMC article. Review.

2

γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.

Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. Ran Y, et al. Among authors: osborne ba. EMBO Mol Med. 2017 Jul;9(7):950-966. doi: 10.15252/emmm.201607265. EMBO Mol Med. 2017. PMID: 28539479 Free PMC article.

3

γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not.

Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Lessard CB, et al. Among authors: osborne ba. Alzheimers Res Ther. 2020 May 19;12(1):61. doi: 10.1186/s13195-020-00622-5. Alzheimers Res Ther. 2020. PMID: 32430033 Free PMC article.

4

Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells.

Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Lessard CB, et al. Among authors: osborne ba. J Biol Chem. 2019 Jul 19;294(29):11276-11285. doi: 10.1074/jbc.RA119.008041. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31167792 Free PMC article.

5

Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology.

Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Das P, et al. Among authors: osborne ba. Mol Neurodegener. 2012 Aug 14;7:39. doi: 10.1186/1750-1326-7-39. Mol Neurodegener. 2012. PMID: 22892055 Free PMC article.

6

Targeting Notch in oncology: the path forward.

Majumder S, Crabtree JS, Golde TE, Minter LM, Osborne BA, Miele L. Majumder S, et al. Among authors: osborne ba. Nat Rev Drug Discov. 2021 Feb;20(2):125-144. doi: 10.1038/s41573-020-00091-3. Epub 2020 Dec 8. Nat Rev Drug Discov. 2021. PMID: 33293690 Review.

7

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21.

Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, Golde TE, Miller SD, Osborne BA. Minter LM, et al. Among authors: osborne ba. Nat Immunol. 2005 Jul;6(7):680-8. Nat Immunol. 2005. PMID: 15991363

8

Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.

Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA. Dongre A, et al. Among authors: osborne ba. Front Immunol. 2014 Feb 12;5:54. doi: 10.3389/fimmu.2014.00054. eCollection 2014. Front Immunol. 2014. PMID: 24611064 Free PMC article.

9

Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.

Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Hossain F, et al. Among authors: osborne ba. Front Immunol. 2018 Jun 4;9:1288. doi: 10.3389/fimmu.2018.01288. eCollection 2018. Front Immunol. 2018. PMID: 29915603 Free PMC article. Review.

10

Notch signaling in cancer.

Miele L, Golde T, Osborne B. Miele L, et al. Curr Mol Med. 2006 Dec;6(8):905-18. doi: 10.2174/156652406779010830. Curr Mol Med. 2006. PMID: 17168741 Review.

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