Ota Y - Search Results

1

Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylase 8-selective inhibitors.

Suzuki T, Muto N, Bando M, Itoh Y, Masaki A, Ri M, Ota Y, Nakagawa H, Iida S, Shirahige K, Miyata N. Suzuki T, et al. Among authors: ota y. ChemMedChem. 2014 Mar;9(3):657-64. doi: 10.1002/cmdc.201300414. Epub 2014 Jan 8. ChemMedChem. 2014. PMID: 24403121

2

Design, synthesis, and biological activity of boronic acid-based histone deacetylase inhibitors.

Suzuki N, Suzuki T, Ota Y, Nakano T, Kurihara M, Okuda H, Yamori T, Tsumoto H, Nakagawa H, Miyata N. Suzuki N, et al. Among authors: ota y. J Med Chem. 2009 May 14;52(9):2909-22. doi: 10.1021/jm900125m. J Med Chem. 2009. PMID: 19419205

3

An unexpected example of protein-templated click chemistry.

Suzuki T, Ota Y, Kasuya Y, Mutsuga M, Kawamura Y, Tsumoto H, Nakagawa H, Finn MG, Miyata N. Suzuki T, et al. Among authors: ota y. Angew Chem Int Ed Engl. 2010 Sep 10;49(38):6817-20. doi: 10.1002/anie.201002205. Angew Chem Int Ed Engl. 2010. PMID: 20715030 No abstract available.

4

Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries.

Suzuki T, Ota Y, Ri M, Bando M, Gotoh A, Itoh Y, Tsumoto H, Tatum PR, Mizukami T, Nakagawa H, Iida S, Ueda R, Shirahige K, Miyata N. Suzuki T, et al. Among authors: ota y. J Med Chem. 2012 Nov 26;55(22):9562-75. doi: 10.1021/jm300837y. Epub 2012 Nov 12. J Med Chem. 2012. PMID: 23116147

5

Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly.

Suzuki T, Kasuya Y, Itoh Y, Ota Y, Zhan P, Asamitsu K, Nakagawa H, Okamoto T, Miyata N. Suzuki T, et al. Among authors: ota y. PLoS One. 2013 Jul 16;8(7):e68669. doi: 10.1371/journal.pone.0068669. Print 2013. PLoS One. 2013. PMID: 23874714 Free PMC article.

6

Identification of novel SIRT2-selective inhibitors using a click chemistry approach.

Tatum PR, Sawada H, Ota Y, Itoh Y, Zhan P, Ieda N, Nakagawa H, Miyata N, Suzuki T. Tatum PR, et al. Among authors: ota y. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1871-4. doi: 10.1016/j.bmcl.2014.03.026. Epub 2014 Mar 20. Bioorg Med Chem Lett. 2014. PMID: 24675380

7

Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

Itoh Y, Ogasawara D, Ota Y, Mizukami T, Suzuki T. Itoh Y, et al. Among authors: ota y. Comput Struct Biotechnol J. 2014 Feb 15;9:e201402002. doi: 10.5936/csbj.201402002. eCollection 2014. Comput Struct Biotechnol J. 2014. PMID: 24757500 Free PMC article.

8

Histone H3 peptide based LSD1-selective inhibitors.

Kakizawa T, Ota Y, Itoh Y, Tsumoto H, Suzuki T. Kakizawa T, et al. Among authors: ota y. Bioorg Med Chem Lett. 2015 May 1;25(9):1925-8. doi: 10.1016/j.bmcl.2015.03.030. Epub 2015 Mar 20. Bioorg Med Chem Lett. 2015. PMID: 25827526

9

Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators.

Itoh Y, Aihara K, Mellini P, Tojo T, Ota Y, Tsumoto H, Solomon VR, Zhan P, Suzuki M, Ogasawara D, Shigenaga A, Inokuma T, Nakagawa H, Miyata N, Mizukami T, Otaka A, Suzuki T. Itoh Y, et al. Among authors: ota y. J Med Chem. 2016 Feb 25;59(4):1531-44. doi: 10.1021/acs.jmedchem.5b01323. Epub 2016 Jan 4. J Med Chem. 2016. PMID: 26700437

10

False HDAC Inhibition by Aurone Compound.

Itoh Y, Suzuki M, Matsui T, Ota Y, Hui Z, Tsubaki K, Suzuki T. Itoh Y, et al. Among authors: ota y. Chem Pharm Bull (Tokyo). 2016;64(8):1124-8. doi: 10.1248/cpb.c16-00123. Chem Pharm Bull (Tokyo). 2016. PMID: 27477650 Free article.

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