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Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.
Cell Metab. 2014 Jun 3;19(6):952-66. doi: 10.1016/j.cmet.2014.04.004. Epub 2014 May 8.
Cell Metab. 2014.
PMID: 24814484
Free PMC article.
Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape.
Shah PP, Donahue G, Otte GL, Capell BC, Nelson DM, Cao K, Aggarwala V, Cruickshanks HA, Rai TS, McBryan T, Gregory BD, Adams PD, Berger SL.
Shah PP, et al. Among authors: otte gl.
Genes Dev. 2013 Aug 15;27(16):1787-99. doi: 10.1101/gad.223834.113. Epub 2013 Aug 9.
Genes Dev. 2013.
PMID: 23934658
Free PMC article.
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Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, Riethman H, Wu H, Schotta G, Garcia BA, Neretti N, Baird DM, Berger SL, Adams PD.
Nelson DM, et al. Among authors: otte gl.
Genome Biol. 2016 Jul 25;17(1):158. doi: 10.1186/s13059-016-1017-x.
Genome Biol. 2016.
PMID: 27457071
Free PMC article.
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Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry.
Lin S, Wein S, Gonzales-Cope M, Otte GL, Yuan ZF, Afjehi-Sadat L, Maile T, Berger SL, Rush J, Lill JR, Arnott D, Garcia BA.
Lin S, et al. Among authors: otte gl.
Mol Cell Proteomics. 2014 Sep;13(9):2450-66. doi: 10.1074/mcp.O113.036459. Epub 2014 Jul 7.
Mol Cell Proteomics. 2014.
PMID: 25000943
Free PMC article.
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Role of lamin b1 in chromatin instability.
Butin-Israeli V, Adam SA, Jain N, Otte GL, Neems D, Wiesmüller L, Berger SL, Goldman RD.
Butin-Israeli V, et al. Among authors: otte gl.
Mol Cell Biol. 2015 Mar;35(5):884-98. doi: 10.1128/MCB.01145-14. Epub 2014 Dec 22.
Mol Cell Biol. 2015.
PMID: 25535332
Free PMC article.
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Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA.
Wan N, Weinberg D, Liu TY, Niehaus K, Ariazi EA, Delubac D, Kannan A, White B, Bailey M, Bertin M, Boley N, Bowen D, Cregg J, Drake AM, Ennis R, Fransen S, Gafni E, Hansen L, Liu Y, Otte GL, Pecson J, Rice B, Sanderson GE, Sharma A, St John J, Tang C, Tzou A, Young L, Putcha G, Haque IS.
Wan N, et al. Among authors: otte gl.
BMC Cancer. 2019 Aug 23;19(1):832. doi: 10.1186/s12885-019-6003-8.
BMC Cancer. 2019.
PMID: 31443703
Free PMC article.
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