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First-in-Human Phase I Clinical Trial of an SFV-Based RNA Replicon Cancer Vaccine against HPV-Induced Cancers.
Komdeur FL, Singh A, van de Wall S, Meulenberg JJM, Boerma A, Hoogeboom BN, Paijens ST, Oyarce C, de Bruyn M, Schuuring E, Regts J, Marra R, Werner N, Sluis J, van der Zee AGJ, Wilschut JC, Allersma DP, van Zanten CJ, Kosterink JGW, Jorritsma-Smit A, Yigit R, Nijman HW, Daemen T. Komdeur FL, et al. Among authors: oyarce c. Mol Ther. 2021 Feb 3;29(2):611-625. doi: 10.1016/j.ymthe.2020.11.002. Epub 2020 Nov 5. Mol Ther. 2021. PMID: 33160073 Free PMC article. Clinical Trial.
A filamentous bacteriophage targeted to carcinoembryonic antigen induces tumor regression in mouse models of colorectal cancer.
Murgas P, Bustamante N, Araya N, Cruz-Gómez S, Durán E, Gaete D, Oyarce C, López E, Herrada AA, Ferreira N, Pieringer H, Lladser A. Murgas P, et al. Among authors: oyarce c. Cancer Immunol Immunother. 2018 Feb;67(2):183-193. doi: 10.1007/s00262-017-2076-x. Epub 2017 Oct 12. Cancer Immunol Immunother. 2018. PMID: 29026949 Free PMC article.
Harnessing DNA-induced immune responses for improving cancer vaccines.
Herrada AA, Rojas-Colonelli N, González-Figueroa P, Roco J, Oyarce C, Ligtenberg MA, Lladser A. Herrada AA, et al. Among authors: oyarce c. Hum Vaccin Immunother. 2012 Nov 1;8(11):1682-93. doi: 10.4161/hv.22345. Epub 2012 Oct 30. Hum Vaccin Immunother. 2012. PMID: 23111166 Free PMC article. Review.
A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination.
Gálvez-Cancino F, Roco J, Rojas-Colonelli N, Flores C, Murgas P, Cruz-Gómez S, Oyarce C, Varas-Godoy M, Sauma D, Lladser A. Gálvez-Cancino F, et al. Among authors: oyarce c. Vaccine. 2017 Jul 24;35(33):4148-4154. doi: 10.1016/j.vaccine.2017.06.041. Epub 2017 Jun 27. Vaccine. 2017. PMID: 28666759
Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8+ T Cell Responses.
Oyarce C, Cruz-Gomez S, Galvez-Cancino F, Vargas P, Moreau HD, Diaz-Valdivia N, Diaz J, Salazar-Onfray FA, Pacheco R, Lennon-Dumenil AM, Quest AFG, Lladser A. Oyarce C, et al. Front Immunol. 2017 Dec 13;8:1794. doi: 10.3389/fimmu.2017.01794. eCollection 2017. Front Immunol. 2017. PMID: 29326695 Free PMC article.
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