In comparison to controls, Fontan patients had elevated levels of multiple cytokines within the inflammatory pathway including Tumor Necrosis Factor-alpha (TNF-alpha) (p < 0.001), Interleukin-6 (IL-6) (p < 0.011), Growth Derived Factor-15 (GDF-15) (p &l
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After matching for age, sex, race, ethnicity, BMI, and significant comorbidities, use of GLP-1R agonists and/or pioglitazone was associated with significant reductions in hospital admissions (GLP-1R: 15.7% vs. 23.5%, risk ratio [RR] 0.67 [95% CI 0.57-0.79; P < 0.001]; p
…In protocol 1, TNCbi significantly increased immediate survival (65 vs 20 %, p < 0.01) while in protocol 2, administration of TNCb
…During low-current ERC, which doubled the metabolic rate ( increased from 192 +/- 23 to 317 +/- 84 ml min(-1), P < 0.01), followed the change in closely (from 5.24 +/- 1.81 to -9.27 +/- 3.60 l min(-1), P < 0.01) in the absence of any chemical error signal occu
…During low-current ERC, which doubled the metabolic rate ( increased from 192 +/- 23 to 317 +/- 84 ml min(-1), P < 0.01), followed
…Survival in this model was very low, reaching 9% at 60 min without any treatment. Methylene blue significantly increased survival (59%, p < .001) at 60 min, versus 37% with HyCo (p < .01). In addition, 8 urethane-anesthetized rats were exposed to a sublethal C
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