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Did you mean p raffin[Author] (142 results)?
Comparative Effects of Low-Dose Rosuvastatin, Placebo, and Dietary Supplements on Lipids and Inflammatory Biomarkers.
Laffin LJ, Bruemmer D, Garcia M, Brennan DM, McErlean E, Jacoby DS, Michos ED, Ridker PM, Wang TY, Watson KE, Hutchinson HG, Nissen SE. Laffin LJ, et al. J Am Coll Cardiol. 2023 Jan 3;81(1):1-12. doi: 10.1016/j.jacc.2022.10.013. Epub 2022 Nov 6. J Am Coll Cardiol. 2023. PMID: 36351465 Free article. Clinical Trial.
The percent LDL-C reduction with rosuvastatin was greater than all supplements and placebo (P < 0.001). The difference in LDL-C reduction with rosuvastatin compared with placebo was -35.2% (95% CI: -41.3% to -29.1%; P < 0.001). ...

The percent LDL-C reduction with rosuvastatin was greater than all supplements and placebo (P < 0.001). The difference in LDL-C re

…
Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients.
Nissen SE, Menon V, Nicholls SJ, Brennan D, Laffin L, Ridker P, Ray KK, Mason D, Kastelein JJP, Cho L, Libby P, Li N, Foody J, Louie MJ, Lincoff AM. Nissen SE, et al. Among authors: laffin l. JAMA. 2023 Jul 11;330(2):131-140. doi: 10.1001/jama.2023.9696. JAMA. 2023. PMID: 37354546 Free PMC article.
Follow-up for a median of 39.9 months was associated with a significant risk reduction for the primary end point (111 events [5.3%] vs 161 events [7.6%]; adjusted hazard ratio [HR], 0.70 [95% CI, 0.55-0.89]; P = .002) and key secondary end points, including the composite o …
Follow-up for a median of 39.9 months was associated with a significant risk reduction for the primary end point (111 events [5.3%] vs 161 e …
Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial.
Laffin LJ, Rodman D, Luther JM, Vaidya A, Weir MR, Rajicic N, Slingsby BT, Nissen SE; Target-HTN Investigators. Laffin LJ, et al. JAMA. 2023 Sep 26;330(12):1140-1150. doi: 10.1001/jama.2023.16029. JAMA. 2023. PMID: 37690061 Free PMC article.
The least-squares mean difference between placebo and treatment in systolic blood pressure was -9.6 mm Hg (90% CI, -15.8 to -3.4 mm Hg; P = .01) for the 50-mg once-daily dose and -7.8 mm Hg (90% CI, -14.1 to -1.5 mm Hg; P = .04) for 100 mg daily. ...
The least-squares mean difference between placebo and treatment in systolic blood pressure was -9.6 mm Hg (90% CI, -15.8 to -3.4 mm Hg; P …
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel.
Scribano CM, Wan J, Esbona K, Tucker JB, Lasek A, Zhou AS, Zasadil LM, Molini R, Fitzgerald J, Lager AM, Laffin JJ, Correia-Staudt K, Wisinski KB, Tevaarwerk AJ, O'Regan R, McGregor SM, Fowler AM, Chappell RJ, Bugni TS, Burkard ME, Weaver BA. Scribano CM, et al. Among authors: laffin jj. Sci Transl Med. 2021 Sep 8;13(610):eabd4811. doi: 10.1126/scitranslmed.abd4811. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516829 Free PMC article.
Near-Fatal Self-Harm Among Canadian Adolescents.
Mitchell RH, Ani C, Cyr C, Irvine J, Joffe AR, Skinner R, Wong S, Stang AS, Laffin M, Korczak DJ. Mitchell RH, et al. Among authors: laffin m. Can J Psychiatry. 2022 Aug;67(8):598-607. doi: 10.1177/07067437211058602. Epub 2021 Nov 30. Can J Psychiatry. 2022. PMID: 34846182 Free PMC article.
Overdose was more common in females (80.8% females vs. 50% males; chi(2) = 7.8 (1), p = .005), whereas hanging was more common in males (35% males vs. 15.1% females, chi(2) = 3.9 (1), p = .04). More females than males had a past psychiatric diagnosis (79% vs. 58%; c …
Overdose was more common in females (80.8% females vs. 50% males; chi(2) = 7.8 (1), p = .005), whereas hanging was more common in mal …
Detection of intracellular virus and viral products.
Laffin J, Lehman JM. Laffin J, et al. Methods Cell Biol. 1994;41:543-57. doi: 10.1016/s0091-679x(08)61739-2. Methods Cell Biol. 1994. PMID: 7861979 Review. No abstract available.
Long-Term Outcomes and Prognostic Factors in Kidney Transplant Recipients with Polycystic Kidney Disease.
Bhutani G, Astor BC, Mandelbrot DA, Mankowski-Gettle L, Ziemlewicz T, Wells SA, Frater-Rubsam L, Horner V, Boyer C, Laffin J, Djamali A. Bhutani G, et al. Among authors: laffin j. Kidney360. 2020 Dec 4;2(2):312-324. doi: 10.34067/KID.0001182019. eCollection 2021 Feb 25. Kidney360. 2020. PMID: 35373032 Free PMC article.
After adjustment for demographic, dialysis, comorbid disease, surgical, and immunologic variables, patients with PKD had a lower risk of DCGF (adjusted hazard ratio [aHR], 0.73; 95% CI, 0.57 to 0.93; P=0.01) and death (aHR, 0.62; 95% CI, 0.51 to 0.75; P<0.001). I …
After adjustment for demographic, dialysis, comorbid disease, surgical, and immunologic variables, patients with PKD had a lower risk of DCG …
High-throughput gene discovery in the rat.
Scheetz TE, Laffin JJ, Berger B, Holte S, Baumes SA, Brown R 2nd, Chang S, Coco J, Conklin J, Crouch K, Donohue M, Doonan G, Estes C, Eyestone M, Fishler K, Gardiner J, Guo L, Johnson B, Keppel C, Kreger R, Lebeck M, Marcelino R, Miljkovich V, Perdue M, Qui L, Rehmann J, Reiter RS, Rhoads B, Schaefer K, Smith C, Sunjevaric I, Trout K, Wu N, Birkett CL, Bischof J, Gackle B, Gavin A, Grundstad AJ, Mokrzycki B, Moressi C, O'Leary B, Pedretti K, Roberts C, Robinson NL, Smith M, Tack D, Trivedi N, Kucaba T, Freeman T, Lin JJ, Bonaldo MF, Casavant TL, Sheffield VC, Soares MB. Scheetz TE, et al. Among authors: laffin jj. Genome Res. 2004 Apr;14(4):733-41. doi: 10.1101/gr.1414204. Genome Res. 2004. PMID: 15060017 Free PMC article.
Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection.
Mocanu V, Park H, Dang J, Hotte N, Thiesen A, Laffin M, Wang H, Birch D, Madsen K. Mocanu V, et al. Among authors: laffin m. Nutrients. 2021 Jun 17;13(6):2069. doi: 10.3390/nu13062069. Nutrients. 2021. PMID: 34204288 Free PMC article.

PRE mice had a trend towards decreased ileal inflammation as evidenced by decreased levels of IL-1beta (p = 0.09), IL-6 (p = 0.03), and TNF-alpha (p < 0.05) compared with mice receiving TBT postoperatively. In contrast, POS mice had trends towards reduced

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PRE mice had a trend towards decreased ileal inflammation as evidenced by decreased levels of IL-1beta (p = 0.09), IL-6 (p = 0 …
A BACH2 Gene Variant Is Associated with Postoperative Recurrence of Crohn's Disease.
Laffin MR, Fedorak RN, Wine E, Dicken B, Madsen KL. Laffin MR, et al. J Am Coll Surg. 2018 May;226(5):902-908. doi: 10.1016/j.jamcollsurg.2018.01.052. Epub 2018 Feb 13. J Am Coll Surg. 2018. PMID: 29452228
Factors associated with increased incidence of recurrence included male sex (p = 0.05) and shortened time to first intestinal operation (5.0 vs 7.3 years; p = 0.03); inflammatory disease behavior was associated with a lower chance of repeat operation (p < …
Factors associated with increased incidence of recurrence included male sex (p = 0.05) and shortened time to first intestinal operati …
57 results