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Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice.
Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. Mazagova M, et al. FASEB J. 2015 Mar;29(3):1043-55. doi: 10.1096/fj.14-259515. Epub 2014 Dec 2. FASEB J. 2015. PMID: 25466902 Free PMC article.
Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice.
Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, Aitken JD, Su Y, Chassaing B, Walters WA, González A, Clemente JC, Cullender TC, Barnich N, Darfeuille-Michaud A, Vijay-Kumar M, Knight R, Ley RE, Gewirtz AT. Carvalho FA, et al. Cell Host Microbe. 2012 Aug 16;12(2):139-52. doi: 10.1016/j.chom.2012.07.004. Epub 2012 Aug 2. Cell Host Microbe. 2012. PMID: 22863420 Free PMC article.
Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.
Dapito DH, Mencin A, Gwak GY, Pradere JP, Jang MK, Mederacke I, Caviglia JM, Khiabanian H, Adeyemi A, Bataller R, Lefkowitch JH, Bower M, Friedman R, Sartor RB, Rabadan R, Schwabe RF. Dapito DH, et al. Cancer Cell. 2012 Apr 17;21(4):504-16. doi: 10.1016/j.ccr.2012.02.007. Cancer Cell. 2012. PMID: 22516259 Free PMC article.