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TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.
Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2215777120. doi: 10.1073/pnas.2215777120. Epub 2023 Aug 16.
Proc Natl Acad Sci U S A. 2023.
PMID: 37585464
Free PMC article.
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D.
Huang P, Cao Q, Xu M, Dong XP.
Huang P, et al.
Cells. 2022 Mar 4;11(5):887. doi: 10.3390/cells11050887.
Cells. 2022.
PMID: 35269509
Free PMC article.
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Endolysosomal TRPMLs in Cancer.
Xu M, Dong XP.
Xu M, et al.
Biomolecules. 2021 Jan 6;11(1):65. doi: 10.3390/biom11010065.
Biomolecules. 2021.
PMID: 33419007
Free PMC article.
Review.
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The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways.
Xu M, Almasi S, Yang Y, Yan C, Sterea AM, Rizvi Syeda AK, Shen B, Richard Derek C, Huang P, Gujar S, Wang J, Zong WX, Trebak M, El Hiani Y, Dong XP.
Xu M, et al.
Cell Calcium. 2019 May;79:80-88. doi: 10.1016/j.ceca.2019.02.010. Epub 2019 Mar 2.
Cell Calcium. 2019.
PMID: 30889511
Free PMC article.
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