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2019 1
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2021 4
2022 1
2023 3
2024 0

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Page 1
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Tejedor JR, Peñarroya A, Gancedo-Verdejo J, Santamarina-Ojeda P, Pérez RF, López-Tamargo S, Díez-Borge A, Alba-Linares JJ, González-Del-Rey N, Urdinguio RG, Mangas C, Roberti A, López V, Morales-Ruiz T, Ariza RR, Roldán-Arjona T, Meijón M, Valledor L, Cañal MJ, Fernández-Martínez D, Fernández-Hevia M, Jiménez-Fonseca P, García-Flórez LJ, Fernández AF, Fraga MF. Tejedor JR, et al. Among authors: santamarina ojeda p. Clin Epigenetics. 2023 Aug 24;15(1):133. doi: 10.1186/s13148-023-01546-1. Clin Epigenetics. 2023. PMID: 37612734 Free PMC article.
Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis.
Roberti A, Tejedor JR, Díaz-Moreno I, López V, Santamarina-Ojeda P, Pérez RF, Urdinguio RG, Concellón C, Martínez-Chantar ML, Fernández-Morera JL, Díaz-Quintana A, Del Amo V, Fernández AF, Fraga MF. Roberti A, et al. Among authors: santamarina ojeda p. Sci Rep. 2023 May 22;13(1):8293. doi: 10.1038/s41598-023-34916-z. Sci Rep. 2023. PMID: 37217546 Free PMC article.
Enhanced Detection of Viral RNA Species Using FokI-Assisted Digestion of DNA Duplexes and DNA/RNA Hybrids.
Tejedor JR, Martín G, Roberti A, Mangas C, Santamarina-Ojeda P, Fernández Pérez R, López V, González Urdinguio R, Alba-Linares JJ, Peñarroya A, Álvarez-Argüelles ME, Boga JA, Fernández Fernández A, Rojo-Alba S, Fernández Fraga M. Tejedor JR, et al. Among authors: santamarina ojeda p. Anal Chem. 2022 May 10;94(18):6760-6770. doi: 10.1021/acs.analchem.2c00407. Epub 2022 Apr 25. Anal Chem. 2022. PMID: 35467835 Free PMC article.
Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse.
Pérez RF, Tejedor JR, Santamarina-Ojeda P, Martínez VL, Urdinguio RG, Villamañán L, Candiota AP, Sarró NMV, Barradas M, Fernandez-Marcos PJ, Serrano M, Fernández AF, Fraga MF. Pérez RF, et al. Among authors: santamarina ojeda p. Mol Biol Evol. 2021 Jul 29;38(8):3415-3435. doi: 10.1093/molbev/msab112. Mol Biol Evol. 2021. PMID: 33871658 Free PMC article.
Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis.
Carella A, Tejedor JR, García MG, Urdinguio RG, Bayón GF, Sierra M, López V, García-Toraño E, Santamarina-Ojeda P, Pérez RF, Bigot T, Mangas C, Corte-Torres MD, Sáenz-de-Santa-María I, Mollejo M, Meléndez B, Astudillo A, Chiara MD, Fernández AF, Fraga MF. Carella A, et al. Among authors: santamarina ojeda p. Int J Cancer. 2020 Jan 15;146(2):373-387. doi: 10.1002/ijc.32520. Epub 2019 Jul 1. Int J Cancer. 2020. PMID: 31211412 Free article.
Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma.
López V, Tejedor JR, Carella A, García MG, Santamarina-Ojeda P, Pérez RF, Mangas C, Urdinguio RG, Aranburu A, de la Nava D, Corte-Torres MD, Astudillo A, Mollejo M, Meléndez B, Fernández AF, Fraga MF. López V, et al. Among authors: santamarina ojeda p. Front Cell Dev Biol. 2021 Aug 10;9:671838. doi: 10.3389/fcell.2021.671838. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34447744 Free PMC article.
Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome.
Esteve-Puig R, Climent F, Piñeyro D, Domingo-Domènech E, Davalos V, Encuentra M, Rea A, Espejo-Herrera N, Soler M, Lopez M, Ortiz-Barahona V, Tapia G, Navarro JT, Cid J, Farré L, Villanueva A, Casanova I, Mangues R, Santamarina-Ojeda P, Fernández AF, Fraga MF, Piris MA, Kol N, Avrahami C, Moshitch-Moshkovitz S, Rechavi G, Sureda A, Esteller M. Esteve-Puig R, et al. Among authors: santamarina ojeda p. Blood. 2021 Feb 18;137(7):994-999. doi: 10.1182/blood.2020005823. Blood. 2021. PMID: 32915956 Free PMC article. No abstract available.
Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia.
Tejedor JR, Bueno C, Vinyoles M, Petazzi P, Agraz-Doblas A, Cobo I, Torres-Ruiz R, Bayón GF, Pérez RF, López-Tamargo S, Gutierrez-Agüera F, Santamarina-Ojeda P, Ramírez-Orellana M, Bardini M, Cazzaniga G, Ballerini P, Schneider P, Stam RW, Varela I, Fraga MF, Fernández AF, Menéndez P. Tejedor JR, et al. Among authors: santamarina ojeda p. J Clin Invest. 2021 Jul 1;131(13):e138833. doi: 10.1172/JCI138833. J Clin Invest. 2021. PMID: 33983906 Free PMC article.