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Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.
Proc Natl Acad Sci U S A. 2019 May 21;116(21):10482-10487. doi: 10.1073/pnas.1903550116. Epub 2019 May 8.
Proc Natl Acad Sci U S A. 2019.
PMID: 31068472
Free PMC article.
A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling.
Lin L, Chamberlain L, Pak ML, Nagarajan A, Gupta R, Zhu LJ, Wright CM, Fong KM, Wajapeyee N, Green MR.
Lin L, et al. Among authors: pak ml.
Cancer Discov. 2014 Oct;4(10):1168-81. doi: 10.1158/2159-8290.CD-13-0747. Epub 2014 Jul 11.
Cancer Discov. 2014.
PMID: 25015643
Free PMC article.
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The CREB Coactivator CRTC2 Is a Lymphoma Tumor Suppressor that Preserves Genome Integrity through Transcription of DNA Mismatch Repair Genes.
Fang M, Pak ML, Chamberlain L, Xing W, Yu H, Green MR.
Fang M, et al. Among authors: pak ml.
Cell Rep. 2015 Jun 9;11(9):1350-7. doi: 10.1016/j.celrep.2015.04.052. Epub 2015 May 21.
Cell Rep. 2015.
PMID: 26004186
Free PMC article.
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PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X.
Vhuiyan MI, Pak ML, Park MA, Thomas D, Lakowski TM, Chalfant CE, Frankel A.
Vhuiyan MI, et al. Among authors: pak ml.
J Biochem. 2017 Jul 1;162(1):17-25. doi: 10.1093/jb/mvw102.
J Biochem. 2017.
PMID: 28057797
Free PMC article.
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A protein arginine N-methyltransferase 1 (PRMT1) and 2 heteromeric interaction increases PRMT1 enzymatic activity.
Pak ML, Lakowski TM, Thomas D, Vhuiyan MI, Hüsecken K, Frankel A.
Pak ML, et al.
Biochemistry. 2011 Sep 27;50(38):8226-40. doi: 10.1021/bi200644c. Epub 2011 Aug 29.
Biochemistry. 2011.
PMID: 21851090
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Förster resonance energy transfer measurements of cofactor-dependent effects on protein arginine N-methyltransferase homodimerization.
Thomas D, Lakowski TM, Pak ML, Kim JJ, Frankel A.
Thomas D, et al. Among authors: pak ml.
Protein Sci. 2010 Nov;19(11):2141-51. doi: 10.1002/pro.492.
Protein Sci. 2010.
PMID: 20812326
Free PMC article.
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MS³ fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM³.
Lakowski TM, Szeitz A, Pak ML, Thomas D, Vhuiyan MI, Kotthaus J, Clement B, Frankel A.
Lakowski TM, et al. Among authors: pak ml.
J Proteomics. 2013 Mar 27;80:43-54. doi: 10.1016/j.jprot.2013.01.003. Epub 2013 Jan 17.
J Proteomics. 2013.
PMID: 23333926
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Arginine methylation in yeast proteins during stationary-phase growth and heat shock.
Lakowski TM, Pak ML, Szeitz A, Thomas D, Vhuiyan MI, Clement B, Frankel A.
Lakowski TM, et al. Among authors: pak ml.
Amino Acids. 2015 Dec;47(12):2561-71. doi: 10.1007/s00726-015-2047-5. Epub 2015 Jul 19.
Amino Acids. 2015.
PMID: 26189025
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