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A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.
Chiarelli LR, Mori G, Orena BS, Esposito M, Lane T, de Jesus Lopes Ribeiro AL, Degiacomi G, Zemanová J, Szádocka S, Huszár S, Palčeková Z, Manfredi M, Gosetti F, Lelièvre J, Ballell L, Kazakova E, Makarov V, Marengo E, Mikusova K, Cole ST, Riccardi G, Ekins S, Pasca MR. Chiarelli LR, et al. Among authors: palcekova z. Sci Rep. 2018 Feb 16;8(1):3187. doi: 10.1038/s41598-018-21614-4. Sci Rep. 2018. PMID: 29453370 Free PMC article.
Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Singh V, Dhar N, Pató J, Kolly GS, Korduláková J, Forbak M, Evans JC, Székely R, Rybniker J, Palčeková Z, Zemanová J, Santi I, Signorino-Gelo F, Rodrigues L, Vocat A, Covarrubias AS, Rengifo MG, Johnsson K, Mowbray S, Buechler J, Delorme V, Brodin P, Knott GW, Aínsa JA, Warner DF, Kéri G, Mikušová K, McKinney JD, Cole ST, Mizrahi V, Hartkoorn RC. Singh V, et al. Among authors: palcekova z. Mol Microbiol. 2017 Jan;103(1):13-25. doi: 10.1111/mmi.13535. Epub 2016 Oct 29. Mol Microbiol. 2017. PMID: 27677649 Free article.
Covalent modifications of polysaccharides in mycobacteria.
Angala SK, Palčeková Z, Belardinelli JM, Jackson M. Angala SK, et al. Among authors: palcekova z. Nat Chem Biol. 2018 Feb 14;14(3):193-198. doi: 10.1038/nchembio.2571. Nat Chem Biol. 2018. PMID: 29443974 Free PMC article.
Unique Features of Mycobacterium abscessus Biofilms Formed in Synthetic Cystic Fibrosis Medium.
Belardinelli JM, Li W, Avanzi C, Angala SK, Lian E, Wiersma CJ, Palčeková Z, Martin KH, Angala B, de Moura VCN, Kerns C, Jones V, Gonzalez-Juarrero M, Davidson RM, Nick JA, Borlee BR, Jackson M. Belardinelli JM, et al. Among authors: palcekova z. Front Microbiol. 2021 Oct 29;12:743126. doi: 10.3389/fmicb.2021.743126. eCollection 2021. Front Microbiol. 2021. PMID: 34777289 Free PMC article.
Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates.
De K, Belardinelli JM, Pandurangan AP, Ehianeta T, Lian E, Palčeková Z, Lam H, Gonzalez-Juarrero M, Bryant JM, Blundell TL, Parkhill J, Floto RA, Lowary TL, Wheat WH, Jackson M. De K, et al. Among authors: palcekova z. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2403206121. doi: 10.1073/pnas.2403206121. Epub 2024 Apr 17. Proc Natl Acad Sci U S A. 2024. PMID: 38630725
Mechanical morphotype switching as an adaptive response in mycobacteria.
Eskandarian HA, Chen YX, Toniolo C, Belardinelli JM, Palcekova Z, Hom L, Ashby PD, Fantner GE, Jackson M, McKinney JD, Javid B. Eskandarian HA, et al. Among authors: palcekova z. Sci Adv. 2024 Jan 5;10(1):eadh7957. doi: 10.1126/sciadv.adh7957. Epub 2024 Jan 3. Sci Adv. 2024. PMID: 38170768 Free PMC article.
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