Palgen JL - Search Results

1

Comparing the Efficacy of Two Generations of EGFR-TKIs: An Integrated Drug-Disease Mechanistic Model Approach in EGFR-Mutated Lung Adenocarcinoma.

Darré H, Masson P, Nativel A, Villain L, Lefaudeux D, Couty C, Martin B, Jacob E, Duruisseaux M, Palgen JL, Monteiro C, L'Hostis A. Darré H, et al. Among authors: palgen jl. Biomedicines. 2024 Mar 21;12(3):704. doi: 10.3390/biomedicines12030704. Biomedicines. 2024. PMID: 38540317 Free PMC article.

2

Empirical methods for the validation of time-to-event mathematical models taking into account uncertainty and variability: application to EGFR + lung adenocarcinoma.

Jacob E, Perrillat-Mercerot A, Palgen JL, L'Hostis A, Ceres N, Boissel JP, Bosley J, Monteiro C, Kahoul R. Jacob E, et al. Among authors: palgen jl. BMC Bioinformatics. 2023 Sep 4;24(1):331. doi: 10.1186/s12859-023-05430-w. BMC Bioinformatics. 2023. PMID: 37667175 Free PMC article.

3

Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma.

L'Hostis A, Palgen JL, Perrillat-Mercerot A, Peyronnet E, Jacob E, Bosley J, Duruisseaux M, Toueg R, Lefèvre L, Kahoul R, Ceres N, Monteiro C. L'Hostis A, et al. Among authors: palgen jl. NPJ Syst Biol Appl. 2023 Jul 31;9(1):37. doi: 10.1038/s41540-023-00292-7. NPJ Syst Biol Appl. 2023. PMID: 37524705 Free PMC article.

4

Identification of human progenitors of exhausted CD8⁺ T cells associated with elevated IFN-γ response in early phase of viral infection.

Cai C, Samir J, Pirozyan MR, Adikari TN, Gupta M, Leung P, Hughes B, Van der Byl W, Rizzetto S, Elthala A, Keoshkerian E, Palgen JL, Peters T, Nguyen THO, Louie R, Kedzierska K, Gaudieri S, Bull RA, Lloyd AR, Luciani F. Cai C, et al. Among authors: palgen jl. Nat Commun. 2022 Dec 7;13(1):7543. doi: 10.1038/s41467-022-35281-7. Nat Commun. 2022. PMID: 36477661 Free PMC article.

5

Innate cell markers that predict anti-HIV neutralizing antibody titers in vaccinated macaques.

Van Tilbeurgh M, Maisonnasse P, Palgen JL, Tolazzi M, Aldon Y, Dereuddre-Bosquet N, Cavarelli M, Beignon AS, Marcos-Lopez E, Gallouet AS, Gilson E, Ozorowski G, Ward AB, Bontjer I, McKay PF, Shattock RJ, Scarlatti G, Sanders RW, Le Grand R. Van Tilbeurgh M, et al. Among authors: palgen jl. Cell Rep Med. 2022 Oct 18;3(10):100751. doi: 10.1016/j.xcrm.2022.100751. Epub 2022 Sep 26. Cell Rep Med. 2022. PMID: 36167072 Free PMC article.

6

Integration of Heterogeneous Biological Data in Multiscale Mechanistic Model Calibration: Application to Lung Adenocarcinoma.

Palgen JL, Perrillat-Mercerot A, Ceres N, Peyronnet E, Coudron M, Tixier E, Illigens BMW, Bosley J, L'Hostis A, Monteiro C. Palgen JL, et al. Acta Biotheor. 2022 Jul 7;70(3):19. doi: 10.1007/s10441-022-09445-3. Acta Biotheor. 2022. PMID: 35796890 Free PMC article.

7

Initial TK-deficient HSV-1 infection in the lip alters contralateral lip challenge immune dynamics.

Rousseau A, Haigh O, Legrand R, Palgen JL, Lemaitre J, Deback C, Oziol N, Lomonte P, Labetoulle M. Rousseau A, et al. Among authors: palgen jl. Sci Rep. 2022 May 19;12(1):8489. doi: 10.1038/s41598-022-12597-4. Sci Rep. 2022. PMID: 35590057 Free PMC article.

8

The Route of Vaccine Administration Determines Whether Blood Neutrophils Undergo Long-Term Phenotypic Modifications.

Feraoun Y, Palgen JL, Joly C, Tchitchek N, Marcos-Lopez E, Dereuddre-Bosquet N, Gallouet AS, Contreras V, Lévy Y, Martinon F, Le Grand R, Beignon AS. Feraoun Y, et al. Among authors: palgen jl. Front Immunol. 2022 Jan 4;12:784813. doi: 10.3389/fimmu.2021.784813. eCollection 2021. Front Immunol. 2022. PMID: 35058925 Free PMC article.

9

Human CD8 T-stem cell memory subsets phenotypic and functional characterization are defined by expression of CD122 or CXCR3.

Zhao Y, Cai C, Samir J, Palgen JL, Keoshkerian E, Li H, Bull RA, Luciani F, An H, Lloyd AR. Zhao Y, et al. Among authors: palgen jl. Eur J Immunol. 2021 Jul;51(7):1732-1747. doi: 10.1002/eji.202049057. Epub 2021 Apr 23. Eur J Immunol. 2021. PMID: 33844287 Free article.

10

Optimize Prime/Boost Vaccine Strategies: Trained Immunity as a New Player in the Game.

Palgen JL, Feraoun Y, Dzangué-Tchoupou G, Joly C, Martinon F, Le Grand R, Beignon AS. Palgen JL, et al. Front Immunol. 2021 Mar 8;12:612747. doi: 10.3389/fimmu.2021.612747. eCollection 2021. Front Immunol. 2021. PMID: 33763063 Free PMC article. Review.

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