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The binding affinity of anti-Aβ1-42 MAb-decorated nanoliposomes to Aβ1-42 peptides in vitro and to amyloid deposits in post-mortem tissue.
Canovi M, Markoutsa E, Lazar AN, Pampalakis G, Clemente C, Re F, Sesana S, Masserini M, Salmona M, Duyckaerts C, Flores O, Gobbi M, Antimisiaris SG. Canovi M, et al. Among authors: pampalakis g. Biomaterials. 2011 Aug;32(23):5489-97. doi: 10.1016/j.biomaterials.2011.04.020. Epub 2011 May 6. Biomaterials. 2011. PMID: 21529932
Targeting the kallikrein-related peptidases for drug development.
Sotiropoulou G, Pampalakis G. Sotiropoulou G, et al. Among authors: pampalakis g. Trends Pharmacol Sci. 2012 Dec;33(12):623-34. doi: 10.1016/j.tips.2012.09.005. Epub 2012 Oct 19. Trends Pharmacol Sci. 2012. PMID: 23089221 Review.
Resistance of naturally secreted α-synuclein to proteolysis.
Ximerakis M, Pampalakis G, Roumeliotis TI, Sykioti VS, Garbis SD, Stefanis L, Sotiropoulou G, Vekrellis K. Ximerakis M, et al. Among authors: pampalakis g. FASEB J. 2014 Jul;28(7):3146-58. doi: 10.1096/fj.13-245852. Epub 2014 Apr 10. FASEB J. 2014. PMID: 24723692
Our results clearly suggest that physiological modifications affect the biochemical behavior of secreted alpha-syn and provide novel insights into mechanisms and potential targets for therapeutic interventions.-Ximerakis, M., Pampalakis, G., Roumeliotis, T. I., Syki …
Our results clearly suggest that physiological modifications affect the biochemical behavior of secreted alpha-syn and provide novel insight …
68 results