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Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.
Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: pan zq. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2007328118. doi: 10.1073/pnas.2007328118. Proc Natl Acad Sci U S A. 2021. PMID: 33602808 Free PMC article.
Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination.
Chong RA, Wu K, Spratt DE, Yang Y, Lee C, Nayak J, Xu M, Elkholi R, Tappin I, Li J, Hurwitz J, Brown BD, Chipuk JE, Chen ZJ, Sanchez R, Shaw GS, Huang L, Pan ZQ. Chong RA, et al. Among authors: pan zq. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8434-9. doi: 10.1073/pnas.1407849111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912152 Free PMC article.
Suramin inhibits cullin-RING E3 ubiquitin ligases.
Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, Zheng JN, Pan ZQ. Wu K, et al. Among authors: pan zq. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2011-8. doi: 10.1073/pnas.1601089113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001857 Free PMC article.
Proximity-induced activation of human Cdc34 through heterologous dimerization.
Gazdoiu S, Yamoah K, Wu K, Escalante CR, Tappin I, Bermudez V, Aggarwal AK, Hurwitz J, Pan ZQ. Gazdoiu S, et al. Among authors: pan zq. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15053-8. doi: 10.1073/pnas.0507646102. Epub 2005 Oct 6. Proc Natl Acad Sci U S A. 2005. PMID: 16210246 Free PMC article.
238 results