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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Mol Cell. 2021 Aug 5;81(15):3128-3144.e7. doi: 10.1016/j.molcel.2021.06.011. Epub 2021 Jul 2.
Mol Cell. 2021.
PMID: 34216544
Free PMC article.
Replication fork stability confers chemoresistance in BRCA-deficient cells.
Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A.
Ray Chaudhuri A, et al. Among authors: panzarino nj.
Nature. 2016 Jul 21;535(7612):382-7. doi: 10.1038/nature18325.
Nature. 2016.
PMID: 27443740
Free PMC article.
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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Turchi JJ, Johnson N, Jonkers J, Rothenberg E, Cantor SB.
Cong K, et al. Among authors: panzarino nj.
Mol Cell. 2021 Aug 5;81(15):3227. doi: 10.1016/j.molcel.2021.07.015.
Mol Cell. 2021.
PMID: 34358459
Free article.
No abstract available.
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Replication Gaps Underlie BRCA Deficiency and Therapy Response.
Panzarino NJ, Krais JJ, Cong K, Peng M, Mosqueda M, Nayak SU, Bond SM, Calvo JA, Doshi MB, Bere M, Ou J, Deng B, Zhu LJ, Johnson N, Cantor SB.
Panzarino NJ, et al.
Cancer Res. 2021 Mar 1;81(5):1388-1397. doi: 10.1158/0008-5472.CAN-20-1602. Epub 2020 Nov 12.
Cancer Res. 2021.
PMID: 33184108
Free PMC article.
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Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress.
Peng M, Cong K, Panzarino NJ, Nayak S, Calvo J, Deng B, Zhu LJ, Morocz M, Hegedus L, Haracska L, Cantor SB.
Peng M, et al. Among authors: panzarino nj.
Cell Rep. 2018 Sep 18;24(12):3251-3261. doi: 10.1016/j.celrep.2018.08.065.
Cell Rep. 2018.
PMID: 30232006
Free PMC article.
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Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.
Chaudhuri AR, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A.
Chaudhuri AR, et al. Among authors: panzarino nj.
Nature. 2016 Nov 17;539(7629):456. doi: 10.1038/nature19826. Epub 2016 Sep 28.
Nature. 2016.
PMID: 27680696
No abstract available.
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