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TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.
Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG. Jayaraman P, et al. Among authors: parihar r. Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018. Oncoimmunology. 2018. PMID: 30288358 Free PMC article.
Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer.
Nalawade SA, Shafer P, Bajgain P, McKenna MK, Ali A, Kelly L, Joubert J, Gottschalk S, Watanabe N, Leen A, Parihar R, Vera Valdes JF, Hoyos V. Nalawade SA, et al. Among authors: parihar r. J Immunother Cancer. 2021 Nov;9(11):e003237. doi: 10.1136/jitc-2021-003237. J Immunother Cancer. 2021. PMID: 34815355 Free PMC article.
Memory NK cells to forget relapsed AML.
Parihar R. Parihar R. Blood. 2022 Mar 17;139(11):1607-1608. doi: 10.1182/blood.2021014906. Blood. 2022. PMID: 35298605 Free article. No abstract available.
Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells.
Shum T, Omer B, Tashiro H, Kruse RL, Wagner DL, Parikh K, Yi Z, Sauer T, Liu D, Parihar R, Castillo P, Liu H, Brenner MK, Metelitsa LS, Gottschalk S, Rooney CM. Shum T, et al. Among authors: parihar r. Cancer Discov. 2017 Nov;7(11):1238-1247. doi: 10.1158/2159-8290.CD-17-0538. Epub 2017 Aug 22. Cancer Discov. 2017. PMID: 28830878 Free PMC article.
Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells.
Omer B, Castillo PA, Tashiro H, Shum T, Huynh MTA, Cardenas M, Tanaka M, Lewis A, Sauer T, Parihar R, Lapteva N, Schmueck-Henneresse M, Mukherjee M, Gottschalk S, Rooney CM. Omer B, et al. Among authors: parihar r. Front Med (Lausanne). 2018 Dec 11;5:343. doi: 10.3389/fmed.2018.00343. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30619856 Free PMC article.
102 results