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Slow TCA flux and ATP production in primary solid tumours but not metastases.
Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD. Bartman CR, et al. Among authors: park nr. Nature. 2023 Feb;614(7947):349-357. doi: 10.1038/s41586-022-05661-6. Epub 2023 Feb 1. Nature. 2023. PMID: 36725930 Free PMC article.
High-throughput in situ perturbation of metabolite levels in the tumor micro-environment reveals favorable metabolic condition for increased fitness of infiltrated T-cells.
Valvo V, Parietti E, Deans K, Ahn SW, Park NR, Ferland B, Thompson D, Dominas C, Bhagavatula SK, Davidson S, Jonas O. Valvo V, et al. Among authors: park nr. Front Cell Dev Biol. 2022 Dec 22;10:1032360. doi: 10.3389/fcell.2022.1032360. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36619865 Free PMC article.
Developmental basis of SHH medulloblastoma heterogeneity.
Gold MP, Ong W, Masteller AM, Ghasemi DR, Galindo JA, Park NR, Huynh NC, Donde A, Pister V, Saurez RA, Vladoiu MC, Hwang GH, Eisemann T, Donovan LK, Walker AD, Benetatos J, Dufour C, Garzia L, Segal RA, Wechsler-Reya RJ, Mesirov JP, Korshunov A, Pajtler KW, Pomeroy SL, Ayrault O, Davidson SM, Cotter JA, Taylor MD, Fraenkel E. Gold MP, et al. Among authors: park nr. Nat Commun. 2024 Jan 8;15(1):270. doi: 10.1038/s41467-023-44300-0. Nat Commun. 2024. PMID: 38191555 Free PMC article.
77 results