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Mouse models of Fanconi anemia.
Parmar K, D'Andrea A, Niedernhofer LJ. Parmar K, et al. Mutat Res. 2009 Jul 31;668(1-2):133-40. doi: 10.1016/j.mrfmmm.2009.03.015. Epub 2009 Apr 10. Mutat Res. 2009. PMID: 19427003 Free PMC article. Review.
Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death.
Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, D'Andrea A, Soiffer R, Weiss JP, Levy O. Guinan EC, et al. Among authors: parmar k. Sci Transl Med. 2011 Nov 23;3(110):110ra118. doi: 10.1126/scitranslmed.3003126. Sci Transl Med. 2011. PMID: 22116933 Free PMC article. Clinical Trial.
Overcoming reprogramming resistance of Fanconi anemia cells.
Müller LU, Milsom MD, Harris CE, Vyas R, Brumme KM, Parmar K, Moreau LA, Schambach A, Park IH, London WB, Strait K, Schlaeger T, Devine AL, Grassman E, D'Andrea A, Daley GQ, Williams DA. Müller LU, et al. Among authors: parmar k. Blood. 2012 Jun 7;119(23):5449-57. doi: 10.1182/blood-2012-02-408674. Epub 2012 Feb 27. Blood. 2012. PMID: 22371882 Free PMC article.
Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.
Ceccaldi R, Parmar K, Mouly E, Delord M, Kim JM, Regairaz M, Pla M, Vasquez N, Zhang QS, Pondarre C, Peffault de Latour R, Gluckman E, Cavazzana-Calvo M, Leblanc T, Larghero J, Grompe M, Socié G, D'Andrea AD, Soulier J. Ceccaldi R, et al. Among authors: parmar k. Cell Stem Cell. 2012 Jul 6;11(1):36-49. doi: 10.1016/j.stem.2012.05.013. Epub 2012 Jun 7. Cell Stem Cell. 2012. PMID: 22683204 Free PMC article.
407 results