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Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.
Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL, Scharenberg AM. Baxter S, et al. Among authors: parmeggiani f. Nucleic Acids Res. 2012 Sep;40(16):7985-8000. doi: 10.1093/nar/gks502. Epub 2012 Jun 7. Nucleic Acids Res. 2012. PMID: 22684507 Free PMC article.
A general computational approach for repeat protein design.
Parmeggiani F, Huang PS, Vorobiev S, Xiao R, Park K, Caprari S, Su M, Seetharaman J, Mao L, Janjua H, Montelione GT, Hunt J, Baker D. Parmeggiani F, et al. J Mol Biol. 2015 Jan 30;427(2):563-75. doi: 10.1016/j.jmb.2014.11.005. Epub 2014 Nov 14. J Mol Biol. 2015. PMID: 25451037 Free PMC article.
Control of repeat-protein curvature by computational protein design.
Park K, Shen BW, Parmeggiani F, Huang PS, Stoddard BL, Baker D. Park K, et al. Among authors: parmeggiani f. Nat Struct Mol Biol. 2015 Feb;22(2):167-74. doi: 10.1038/nsmb.2938. Epub 2015 Jan 12. Nat Struct Mol Biol. 2015. PMID: 25580576 Free PMC article.
Exploring the repeat protein universe through computational protein design.
Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Brunette TJ, et al. Among authors: parmeggiani f. Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16. Nature. 2015. PMID: 26675729 Free PMC article.
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
Reichen C, Hansen S, Forzani C, Honegger A, Fleishman SJ, Zhou T, Parmeggiani F, Ernst P, Madhurantakam C, Ewald C, Mittl PRE, Zerbe O, Baker D, Caflisch A, Plückthun A. Reichen C, et al. Among authors: parmeggiani f. J Mol Biol. 2016 Nov 6;428(22):4467-4489. doi: 10.1016/j.jmb.2016.09.012. Epub 2016 Sep 21. J Mol Biol. 2016. PMID: 27664438
Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.
Mills JH, Sheffler W, Ener ME, Almhjell PJ, Oberdorfer G, Pereira JH, Parmeggiani F, Sankaran B, Zwart PH, Baker D. Mills JH, et al. Among authors: parmeggiani f. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15012-15017. doi: 10.1073/pnas.1600188113. Epub 2016 Dec 8. Proc Natl Acad Sci U S A. 2016. PMID: 27940918 Free PMC article.
Computational design of self-assembling cyclic protein homo-oligomers.
Fallas JA, Ueda G, Sheffler W, Nguyen V, McNamara DE, Sankaran B, Pereira JH, Parmeggiani F, Brunette TJ, Cascio D, Yeates TR, Zwart P, Baker D. Fallas JA, et al. Among authors: parmeggiani f. Nat Chem. 2017 Apr;9(4):353-360. doi: 10.1038/nchem.2673. Epub 2016 Dec 5. Nat Chem. 2017. PMID: 28338692 Free PMC article.
168 results