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Clinical and molecular profile of a new series of patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: inconsistent correlation between forkhead box protein 3 expression and disease severity.
Gambineri E, Perroni L, Passerini L, Bianchi L, Doglioni C, Meschi F, Bonfanti R, Sznajer Y, Tommasini A, Lawitschka A, Junker A, Dunstheimer D, Heidemann PH, Cazzola G, Cipolli M, Friedrich W, Janic D, Azzi N, Richmond E, Vignola S, Barabino A, Chiumello G, Azzari C, Roncarolo MG, Bacchetta R. Gambineri E, et al. Among authors: passerini l. J Allergy Clin Immunol. 2008 Dec;122(6):1105-1112.e1. doi: 10.1016/j.jaci.2008.09.027. Epub 2008 Oct 25. J Allergy Clin Immunol. 2008. PMID: 18951619
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, Ziegler SF, Roncarolo MG, Levings MK. Allan SE, et al. Among authors: passerini l. J Clin Invest. 2005 Nov;115(11):3276-84. doi: 10.1172/JCI24685. Epub 2005 Oct 6. J Clin Invest. 2005. PMID: 16211090 Free PMC article.
Defective regulatory and effector T cell functions in patients with FOXP3 mutations.
Bacchetta R, Passerini L, Gambineri E, Dai M, Allan SE, Perroni L, Dagna-Bricarelli F, Sartirana C, Matthes-Martin S, Lawitschka A, Azzari C, Ziegler SF, Levings MK, Roncarolo MG. Bacchetta R, et al. Among authors: passerini l. J Clin Invest. 2006 Jun;116(6):1713-22. doi: 10.1172/JCI25112. J Clin Invest. 2006. PMID: 16741580 Free PMC article.
Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations.
Di Nunzio S, Cecconi M, Passerini L, McMurchy AN, Baron U, Turbachova I, Vignola S, Valencic E, Tommasini A, Junker A, Cazzola G, Olek S, Levings MK, Perroni L, Roncarolo MG, Bacchetta R. Di Nunzio S, et al. Among authors: passerini l. Blood. 2009 Nov 5;114(19):4138-41. doi: 10.1182/blood-2009-04-214593. Epub 2009 Sep 8. Blood. 2009. PMID: 19738030 Free article.
Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.
McMurchy AN, Gillies J, Allan SE, Passerini L, Gambineri E, Roncarolo MG, Bacchetta R, Levings MK. McMurchy AN, et al. Among authors: passerini l. J Allergy Clin Immunol. 2010 Dec;126(6):1242-51. doi: 10.1016/j.jaci.2010.09.001. Epub 2010 Oct 30. J Allergy Clin Immunol. 2010. PMID: 21036387
84 results