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Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-alpha and the transcriptional repressor PLZF.
Buluwela L, Pike J, Mazhar D, Kamalati T, Hart SM, Al-Jehani R, Yahaya H, Patel N, Sarwar N, Heathcote DA, Schwickerath O, Phoenix F, Hill R, Aboagye E, Shousha S, Waxman J, Lemoine NR, Zelent A, Coombes RC, Ali S. Buluwela L, et al. Among authors: patel n. Gene Ther. 2005 Mar;12(5):452-60. doi: 10.1038/sj.gt.3302421. Gene Ther. 2005. PMID: 15647773
The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer.
Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, Viola P, Green A, Nolan C, Ellis IO, Rakha EA, Shousha S, Lam EW, Győrffy B, Lupien M, Coombes RC. Magnani L, et al. Among authors: patel n. Oncotarget. 2015 Sep 8;6(26):21878-91. doi: 10.18632/oncotarget.4243. Oncotarget. 2015. PMID: 26215677 Free PMC article.
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.
Nguyen VT, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, Frige G, Minucci S, Coombes RC, Magnani L. Nguyen VT, et al. Among authors: patel n. Nat Commun. 2015 Nov 27;6:10044. doi: 10.1038/ncomms10044. Nat Commun. 2015. PMID: 26610607 Free PMC article.
Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer.
Patel H, Abduljabbar R, Lai CF, Periyasamy M, Harrod A, Gemma C, Steel JH, Patel N, Busonero C, Jerjees D, Remenyi J, Smith S, Gomm JJ, Magnani L, Győrffy B, Jones LJ, Fuller-Pace F, Shousha S, Buluwela L, Rakha EA, Ellis IO, Coombes RC, Ali S. Patel H, et al. Among authors: patel n. Clin Cancer Res. 2016 Dec 1;22(23):5929-5938. doi: 10.1158/1078-0432.CCR-15-1104. Epub 2016 Jun 14. Clin Cancer Res. 2016. PMID: 27301701 Free PMC article.
Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.
Nguyen VTM, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Rodriguez-Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, Frige G, Minucci S, Coombes RC, Magnani L. Nguyen VTM, et al. Among authors: patel n. Nat Commun. 2019 Aug 6;10(1):3505. doi: 10.1038/s41467-019-11569-z. Nat Commun. 2019. PMID: 31388012 Free PMC article.
Loss of O⁶-methylguanine-DNA methyltransferase confers collateral sensitivity to carmustine in topoisomerase II-mediated doxorubicin resistant triple negative breast cancer cells.
Raguz S, Adams C, Masrour N, Rasul S, Papoutsoglou P, Hu Y, Cazzanelli G, Zhou Y, Patel N, Coombes C, Yagüe E. Raguz S, et al. Among authors: patel n. Biochem Pharmacol. 2013 Jan 15;85(2):186-96. doi: 10.1016/j.bcp.2012.10.020. Epub 2012 Oct 30. Biochem Pharmacol. 2013. PMID: 23122841 Free article.
SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer.
Perone Y, Farrugia AJ, Rodríguez-Meira A, Győrffy B, Ion C, Uggetti A, Chronopoulos A, Marrazzo P, Faronato M, Shousha S, Davies C, Steel JH, Patel N, Del Rio Hernandez A, Coombes C, Pruneri G, Lim A, Calvo F, Magnani L. Perone Y, et al. Among authors: patel n. Nat Commun. 2019 May 9;10(1):2115. doi: 10.1038/s41467-019-09676-y. Nat Commun. 2019. PMID: 31073170 Free PMC article.
9,158 results