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Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.
Le X, Negrao MV, Reuben A, Federico L, Diao L, McGrail D, Nilsson M, Robichaux J, Munoz IG, Patel S, Elamin Y, Fan YH, Lee WC, Parra E, Solis Soto LM, Chen R, Li J, Karpinets T, Khairullah R, Kadara H, Behrens C, Sepesi B, Wang R, Zhu M, Wang L, Vaporciyan A, Roth J, Swisher S, Haymaker C, Zhang J, Wang J, Wong KK, Byers LA, Bernatchez C, Zhang J, Wistuba II, Gibbons DL, Akbay EA, Heymach JV. Le X, et al. Among authors: patel s. J Thorac Oncol. 2021 Apr;16(4):583-600. doi: 10.1016/j.jtho.2020.12.010. Epub 2020 Dec 31. J Thorac Oncol. 2021. PMID: 33388477 Free article.
Altered Regulation of HIF-1α in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype.
Nilsson MB, Robichaux J, Herynk MH, Cascone T, Le X, Elamin Y, Patel S, Zhang F, Xu L, Hu L, Diao L, Shen L, He J, Yu X, Nikolinakos P, Saintigny P, Fang B, Girard L, Wang J, Minna JD, Wistuba II, Heymach JV. Nilsson MB, et al. Among authors: patel s. J Thorac Oncol. 2021 Mar;16(3):439-451. doi: 10.1016/j.jtho.2020.11.022. Epub 2020 Dec 9. J Thorac Oncol. 2021. PMID: 33309987 Free PMC article.
Estrogen Promotes Resistance to Bevacizumab in Murine Models of NSCLC.
Patel SA, Herynk MH, Cascone T, Saigal B, Nilsson MB, Tran H, Ramachandran S, Diao L, Wang J, Le X, Minna J, Wistuba II, Heymach JV. Patel SA, et al. J Thorac Oncol. 2021 Dec;16(12):2051-2064. doi: 10.1016/j.jtho.2021.07.007. Epub 2021 Jul 24. J Thorac Oncol. 2021. PMID: 34311109 Free PMC article.
Limited Benefit from the Addition of Immunotherapy to Chemotherapy in TKI-Refractory EGFR-Mutant Lung Adenocarcinoma.
Hong L, Lewis WE, Nilsson M, Patel S, Varghese S, Rivera MJ, Du RR, Chen P, Kemp HN, Rinsurongkawong W, Heeke S, Spelman AR, Elamin YY, Negrao MV, Sepesi B, Gibbons DL, Lee JJ, Wu J, Vokes NI, Heymach JV, Zhang J, Le X. Hong L, et al. Among authors: patel s. Cancers (Basel). 2022 Jul 17;14(14):3473. doi: 10.3390/cancers14143473. Cancers (Basel). 2022. PMID: 35884533 Free PMC article.
CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance.
Nilsson MB, Yang Y, Heeke S, Patel SA, Poteete A, Udagawa H, Elamin YY, Moran CA, Kashima Y, Arumugam T, Yu X, Ren X, Diao L, Shen L, Wang Q, Zhang M, Robichaux JP, Shi C, Pfeil AN, Tran H, Gibbons DL, Bock J, Wang J, Minna JD, Kobayashi SS, Le X, Heymach JV. Nilsson MB, et al. Among authors: patel sa. Cancer Cell. 2023 Feb 13;41(2):340-355.e6. doi: 10.1016/j.ccell.2023.01.007. Cancer Cell. 2023. PMID: 36787696 Free PMC article.
ATM Mutations Associate with Distinct Co-Mutational Patterns and Therapeutic Vulnerabilities in NSCLC.
Vokes NI, Galan Cobo A, Fernandez-Chas M, Molkentine D, Treviño S 3rd, Druker V, Qian Y, Patel S, Schmidt S, Hong L, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee JJ, Negrao MV, Gibbons DL, Vaporciyan A, Le X, Wu J, Zhang J, Rigney U, Iyer S, Dean E, Heymach JV. Vokes NI, et al. Among authors: patel s. Clin Cancer Res. 2023 Dec 1;29(23):4958-4972. doi: 10.1158/1078-0432.CCR-23-1122. Clin Cancer Res. 2023. PMID: 37733794 Free PMC article.
Plasmoid Formation and Strong Radiative Cooling in a Driven Magnetic Reconnection Experiment.
Datta R, Chandler K, Myers CE, Chittenden JP, Crilly AJ, Aragon C, Ampleford DJ, Banasek JT, Edens A, Fox WR, Hansen SB, Harding EC, Jennings CA, Ji H, Kuranz CC, Lebedev SV, Looker Q, Patel SG, Porwitzky A, Shipley GA, Uzdensky DA, Yager-Elorriaga DA, Hare JD. Datta R, et al. Among authors: patel sg. Phys Rev Lett. 2024 Apr 12;132(15):155102. doi: 10.1103/PhysRevLett.132.155102. Phys Rev Lett. 2024. PMID: 38683000
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