Payan DG - Search Results

1

Targeting Syk as a treatment for allergic and autoimmune disorders.

Wong BR, Grossbard EB, Payan DG, Masuda ES. Wong BR, et al. Among authors: payan dg. Expert Opin Investig Drugs. 2004 Jul;13(7):743-62. doi: 10.1517/13543784.13.7.743. Expert Opin Investig Drugs. 2004. PMID: 15212616 Review.

2

Identification of the Syk kinase inhibitor R112 by a human mast cell screen.

Rossi AB, Herlaar E, Braselmann S, Huynh S, Taylor V, Frances R, Issakani SD, Argade A, Singh R, Payan DG, Masuda ES. Rossi AB, et al. Among authors: payan dg. J Allergy Clin Immunol. 2006 Sep;118(3):749-55. doi: 10.1016/j.jaci.2006.05.023. Epub 2006 Jul 28. J Allergy Clin Immunol. 2006. PMID: 16950297

3

Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor.

Pine PR, Chang B, Schoettler N, Banquerigo ML, Wang S, Lau A, Zhao F, Grossbard EB, Payan DG, Brahn E. Pine PR, et al. Among authors: payan dg. Clin Immunol. 2007 Sep;124(3):244-57. doi: 10.1016/j.clim.2007.03.543. Epub 2007 May 29. Clin Immunol. 2007. PMID: 17537677

4

Discovery and development of spleen tyrosine kinase (SYK) inhibitors.

Singh R, Masuda ES, Payan DG. Singh R, et al. Among authors: payan dg. J Med Chem. 2012 Apr 26;55(8):3614-43. doi: 10.1021/jm201271b. Epub 2012 Feb 14. J Med Chem. 2012. PMID: 22257213 No abstract available.

5

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation.

Braselmann S, Taylor V, Zhao H, Wang S, Sylvain C, Baluom M, Qu K, Herlaar E, Lau A, Young C, Wong BR, Lovell S, Sun T, Park G, Argade A, Jurcevic S, Pine P, Singh R, Grossbard EB, Payan DG, Masuda ES. Braselmann S, et al. Among authors: payan dg. J Pharmacol Exp Ther. 2006 Dec;319(3):998-1008. doi: 10.1124/jpet.106.109058. Epub 2006 Aug 31. J Pharmacol Exp Ther. 2006. PMID: 16946104 Clinical Trial.

6

A class of small molecules that inhibit TNFalpha-induced survival and death pathways via prevention of interactions between TNFalphaRI, TRADD, and RIP1.

Gururaja TL, Yung S, Ding R, Huang J, Zhou X, McLaughlin J, Daniel-Issakani S, Singh R, Cooper RD, Payan DG, Masuda ES, Kinoshita T. Gururaja TL, et al. Among authors: payan dg. Chem Biol. 2007 Oct;14(10):1105-18. doi: 10.1016/j.chembiol.2007.08.012. Chem Biol. 2007. PMID: 17961823

7

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus.

Bahjat FR, Pine PR, Reitsma A, Cassafer G, Baluom M, Grillo S, Chang B, Zhao FF, Payan DG, Grossbard EB, Daikh DI. Bahjat FR, et al. Among authors: payan dg. Arthritis Rheum. 2008 May;58(5):1433-44. doi: 10.1002/art.23428. Arthritis Rheum. 2008. PMID: 18438845 Free article.

8

JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.

Chang BY, Zhao F, He X, Ren H, Braselmann S, Taylor V, Wicks J, Payan DG, Grossbard EB, Pine PR, Bullard DC. Chang BY, et al. Among authors: payan dg. J Immunol. 2009 Aug 1;183(3):2183-92. doi: 10.4049/jimmunol.0804063. Epub 2009 Jul 13. J Immunol. 2009. PMID: 19596999

9

Targeting autoimmunity: strategies and tactics.

Masuda ES, Payan DG. Masuda ES, et al. Among authors: payan dg. Drug Discov Today. 2014 Aug;19(8):1193-4. doi: 10.1016/j.drudis.2014.05.024. Epub 2014 Jun 2. Drug Discov Today. 2014. PMID: 24886764 No abstract available.

10

Design, synthesis of diaminopyrimidine inhibitors targeting IgE- and IgG-mediated activation of Fc receptor signaling.

Argade A, Bhamidipati S, Li H, Sylvain C, Clough J, Carroll D, Keim H, Braselmann S, Taylor V, Zhao H, Herlaar E, Issakani SD, Wong BR, Masuda ES, Payan DG, Singh R. Argade A, et al. Among authors: payan dg. Bioorg Med Chem Lett. 2015;25(10):2122-8. doi: 10.1016/j.bmcl.2015.03.072. Epub 2015 Apr 1. Bioorg Med Chem Lett. 2015. PMID: 25891105

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