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Wnt-β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression.
Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, Mathur PS, Emmanuel AO, Osman A, Krishnan M, Morin SB, Pearson AT, Sweis RF, Pekow J, Weber CR, Khazaie K, Gounari F. Quandt J, et al. Among authors: pearson at. Nat Immunol. 2021 Apr;22(4):471-484. doi: 10.1038/s41590-021-00889-2. Epub 2021 Mar 4. Nat Immunol. 2021. PMID: 33664518 Free PMC article.
AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling.
Ferrarotto R, Mishra V, Herz E, Yaacov A, Solomon O, Rauch R, Mondshine A, Motin M, Leibovich-Rivkin T, Davis M, Kaye J, Weber CR, Shen L, Pearson AT, Rosenberg AJ, Chen X, Singh A, Aster JC, Agrawal N, Izumchenko E. Ferrarotto R, et al. Among authors: pearson at. Cell Death Dis. 2022 Aug 5;13(8):678. doi: 10.1038/s41419-022-05133-9. Cell Death Dis. 2022. PMID: 35931701 Free PMC article.
Author Correction: Pan-cancer image-based detection of clinically actionable genetic alterations.
Kather JN, Heij LR, Grabsch HI, Loeffler C, Echle A, Muti HS, Krause J, Niehues JM, Sommer KAJ, Bankhead P, Kooreman LFS, Schulte JJ, Cipriani NA, Buelow RD, Boor P, Ortiz-Brüchle N, Hanby AM, Speirs V, Kochanny S, Patnaik A, Srisuwananukorn A, Brenner H, Hoffmeister M, van den Brandt PA, Jäger D, Trautwein C, Pearson AT, Luedde T. Kather JN, et al. Among authors: pearson at. Nat Cancer. 2020 Nov;1(11):1129. doi: 10.1038/s43018-020-00149-6. Nat Cancer. 2020. PMID: 35122072 No abstract available.
Ovarian cancer through a multi-modal lens.
Hieromnimon HM, Pearson AT. Hieromnimon HM, et al. Among authors: pearson at. Nat Cancer. 2022 Jun;3(6):662-664. doi: 10.1038/s43018-022-00397-8. Nat Cancer. 2022. PMID: 35764744 No abstract available.
107 results