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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.
Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, Glinsky G, Scudiero D, Sausville E, Salvesen G, Nefzi A, Ostresh JM, Houghten RA, Reed JC. Schimmer AD, et al. Among authors: pedersen im. Cancer Cell. 2004 Jan;5(1):25-35. doi: 10.1016/s1535-6108(03)00332-5. Cancer Cell. 2004. PMID: 14749124 Free article.
The triterpenoid CDDO induces apoptosis in refractory CLL B cells.
Pedersen IM, Kitada S, Schimmer A, Kim Y, Zapata JM, Charboneau L, Rassenti L, Andreeff M, Bennett F, Sporn MB, Liotta LD, Kipps TJ, Reed JC. Pedersen IM, et al. Blood. 2002 Oct 15;100(8):2965-72. doi: 10.1182/blood-2002-04-1174. Blood. 2002. PMID: 12351409 Free article.
A unified model for apical caspase activation.
Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM, Ricci JE, Edris WA, Sutherlin DP, Green DR, Salvesen GS. Boatright KM, et al. Among authors: pedersen im. Mol Cell. 2003 Feb;11(2):529-41. doi: 10.1016/s1097-2765(03)00051-0. Mol Cell. 2003. PMID: 12620239 Free article.
Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases.
Miletic AV, Anzelon-Mills AN, Mills DM, Omori SA, Pedersen IM, Shin DM, Ravetch JV, Bolland S, Morse HC 3rd, Rickert RC. Miletic AV, et al. Among authors: pedersen im. J Exp Med. 2010 Oct 25;207(11):2407-20. doi: 10.1084/jem.20091962. Epub 2010 Oct 18. J Exp Med. 2010. PMID: 20956547 Free PMC article.
35 results