Pedersen MT - Search Results

1

DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.

Scourzic L, Couronné L, Pedersen MT, Della Valle V, Diop M, Mylonas E, Calvo J, Mouly E, Lopez CK, Martin N, Fontenay M, Bender A, Guibert S, Dubreuil P, Dessen P, Droin N, Pflumio F, Weber M, Gaulard P, Helin K, Mercher T, Bernard OA. Scourzic L, et al. Among authors: pedersen mt. Leukemia. 2016 Jun;30(6):1388-98. doi: 10.1038/leu.2016.29. Epub 2016 Feb 15. Leukemia. 2016. PMID: 26876596 Free PMC article.

2

Histone demethylases in development and disease.

Pedersen MT, Helin K. Pedersen MT, et al. Trends Cell Biol. 2010 Nov;20(11):662-71. doi: 10.1016/j.tcb.2010.08.011. Epub 2010 Sep 20. Trends Cell Biol. 2010. PMID: 20863703 Review.

3

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.

Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, Rappsilber J, Helin K. Williams K, et al. Among authors: pedersen mt. Nature. 2011 May 19;473(7347):343-8. doi: 10.1038/nature10066. Epub 2011 Apr 13. Nature. 2011. PMID: 21490601 Free PMC article.

4

Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma.

Asmar F, Punj V, Christensen J, Pedersen MT, Pedersen A, Nielsen AB, Hother C, Ralfkiaer U, Brown P, Ralfkiaer E, Helin K, Grønbæk K. Asmar F, et al. Among authors: pedersen mt, pedersen a. Haematologica. 2013 Dec;98(12):1912-20. doi: 10.3324/haematol.2013.088740. Epub 2013 Jul 5. Haematologica. 2013. PMID: 23831920 Free PMC article. Clinical Trial.

5

The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development.

Pedersen MT, Agger K, Laugesen A, Johansen JV, Cloos PA, Christensen J, Helin K. Pedersen MT, et al. Mol Cell Biol. 2014 Mar;34(6):1031-45. doi: 10.1128/MCB.00864-13. Epub 2014 Jan 6. Mol Cell Biol. 2014. PMID: 24396064 Free PMC article.

6

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.

Rasmussen KD, Jia G, Johansen JV, Pedersen MT, Rapin N, Bagger FO, Porse BT, Bernard OA, Christensen J, Helin K. Rasmussen KD, et al. Among authors: pedersen mt. Genes Dev. 2015 May 1;29(9):910-22. doi: 10.1101/gad.260174.115. Epub 2015 Apr 17. Genes Dev. 2015. PMID: 25886910 Free PMC article.

7

Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.

Agger K, Miyagi S, Pedersen MT, Kooistra SM, Johansen JV, Helin K. Agger K, et al. Among authors: pedersen mt. Genes Dev. 2016 Jun 1;30(11):1278-88. doi: 10.1101/gad.280495.116. Epub 2016 Jun 2. Genes Dev. 2016. PMID: 27257215 Free PMC article.

8

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.

Pedersen MT, Kooistra SM, Radzisheuskaya A, Laugesen A, Johansen JV, Hayward DG, Nilsson J, Agger K, Helin K. Pedersen MT, et al. EMBO J. 2016 Jul 15;35(14):1550-64. doi: 10.15252/embj.201593317. Epub 2016 Jun 6. EMBO J. 2016. PMID: 27266524 Free PMC article.

9

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells.

Rasmussen KD, Berest I, Keβler S, Nishimura K, Simón-Carrasco L, Vassiliou GS, Pedersen MT, Christensen J, Zaugg JB, Helin K. Rasmussen KD, et al. Among authors: pedersen mt. Genome Res. 2019 Apr;29(4):564-575. doi: 10.1101/gr.239277.118. Epub 2019 Feb 22. Genome Res. 2019. PMID: 30796038 Free PMC article.

10

Cell biology: Unconventional translation in cancer.

Pedersen MT, Jensen KB. Pedersen MT, et al. Nature. 2017 Jan 11;541(7638):471-472. doi: 10.1038/nature21115. Nature. 2017. PMID: 28117446 No abstract available.

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