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Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L. Wu W, et al. Among authors: pei h. Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7. Carcinogenesis. 2013. PMID: 23471882
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