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Bcl-2 Antiapoptotic Family Proteins and Chemoresistance in Cancer.
Maji S, Panda S, Samal SK, Shriwas O, Rath R, Pellecchia M, Emdad L, Das SK, Fisher PB, Dash R. Maji S, et al. Among authors: pellecchia m. Adv Cancer Res. 2018;137:37-75. doi: 10.1016/bs.acr.2017.11.001. Epub 2017 Dec 6. Adv Cancer Res. 2018. PMID: 29405977 Review.
Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins.
Wei J, Kitada S, Rega MF, Emdadi A, Yuan H, Cellitti J, Stebbins JL, Zhai D, Sun J, Yang L, Dahl R, Zhang Z, Wu B, Wang S, Reed TA, Wang HG, Lawrence N, Sebti S, Reed JC, Pellecchia M. Wei J, et al. Among authors: pellecchia m. Mol Cancer Ther. 2009 Apr;8(4):904-13. doi: 10.1158/1535-7163.MCT-08-1050. Mol Cancer Ther. 2009. PMID: 19372563 Free PMC article.
Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine.
Dash R, Richards JE, Su ZZ, Bhutia SK, Azab B, Rahmani M, Dasmahapatra G, Yacoub A, Dent P, Dmitriev IP, Curiel DT, Grant S, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Dash R, et al. Among authors: pellecchia m. Cancer Res. 2010 Jun 15;70(12):5034-45. doi: 10.1158/0008-5472.CAN-10-0563. Epub 2010 May 25. Cancer Res. 2010. PMID: 20501829 Free PMC article.
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Dash R, et al. Among authors: pellecchia m. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8785-90. doi: 10.1073/pnas.1100769108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555592 Free PMC article.
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Azab B, Dash R, Das SK, Bhutia SK, Shen XN, Quinn BA, Sarkar S, Wang XY, Hedvat M, Dmitriev IP, Curiel DT, Grant S, Dent P, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Azab B, et al. Among authors: pellecchia m. J Cell Physiol. 2012 May;227(5):2145-53. doi: 10.1002/jcp.22947. J Cell Physiol. 2012. PMID: 21780116 Free PMC article.
Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics.
Kim K, Lee SG, Kegelman TP, Su ZZ, Das SK, Dash R, Dasgupta S, Barral PM, Hedvat M, Diaz P, Reed JC, Stebbins JL, Pellecchia M, Sarkar D, Fisher PB. Kim K, et al. Among authors: pellecchia m. J Cell Physiol. 2011 Oct;226(10):2484-93. doi: 10.1002/jcp.22609. J Cell Physiol. 2011. PMID: 21792905 Free PMC article. Review.
460 results