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Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.
Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. Li S, et al. Among authors: pellegrini m. J Clin Invest. 2022 Jan 18;132(2):e149711. doi: 10.1172/JCI149711. J Clin Invest. 2022. PMID: 34813507 Free PMC article.
Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.
Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT. Vincent JJ, et al. Among authors: pellegrini m. Cell Stem Cell. 2013 Apr 4;12(4):470-8. doi: 10.1016/j.stem.2013.01.016. Epub 2013 Feb 14. Cell Stem Cell. 2013. PMID: 23415914 Free PMC article.
Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells.
Huang K, Wu Z, Liu Z, Hu G, Yu J, Chang KH, Kim KP, Le T, Faull KF, Rao N, Gennery A, Xue Z, Wang CY, Pellegrini M, Fan G. Huang K, et al. Among authors: pellegrini m. Hum Mol Genet. 2014 Dec 15;23(24):6448-57. doi: 10.1093/hmg/ddu365. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027325 Free PMC article.
A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase.
Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K. Minkovsky A, et al. Among authors: pellegrini m. Epigenetics Chromatin. 2015 Oct 13;8:42. doi: 10.1186/s13072-015-0034-4. eCollection 2015. Epigenetics Chromatin. 2015. PMID: 26468331 Free PMC article.
A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Soragni A, Janzen DM, Johnson LM, Lindgren AG, Thai-Quynh Nguyen A, Tiourin E, Soriaga AB, Lu J, Jiang L, Faull KF, Pellegrini M, Memarzadeh S, Eisenberg DS. Soragni A, et al. Among authors: pellegrini m. Cancer Cell. 2016 Jan 11;29(1):90-103. doi: 10.1016/j.ccell.2015.12.002. Epub 2015 Dec 31. Cancer Cell. 2016. PMID: 26748848 Free PMC article.
1,651 results