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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun. 2023 Sep 29;14(1):6091. doi: 10.1038/s41467-023-41821-6.
Nat Commun. 2023.
PMID: 37773238
Free PMC article.
Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.
Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, James LI, Frye SV.
Perfetti MT, et al.
ACS Chem Biol. 2015 Apr 17;10(4):1072-81. doi: 10.1021/cb500956g. Epub 2015 Jan 28.
ACS Chem Biol. 2015.
PMID: 25590533
Free PMC article.
Item in Clipboard
Low utilization of circulating glucose after food withdrawal in Snell dwarf mice.
Brooks NL, Trent CM, Raetzsch CF, Flurkey K, Boysen G, Perfetti MT, Jeong YC, Klebanov S, Patel KB, Khodush VR, Kupper LL, Carling D, Swenberg JA, Harrison DE, Combs TP.
Brooks NL, et al. Among authors: perfetti mt.
J Biol Chem. 2007 Nov 30;282(48):35069-77. doi: 10.1074/jbc.M700484200. Epub 2007 Sep 28.
J Biol Chem. 2007.
PMID: 17905742
Free article.
Item in Clipboard
Do low levels of circulating adiponectin represent a biomarker or just another risk factor for the metabolic syndrome?
Brooks NL, Moore KS, Clark RD, Perfetti MT, Trent CM, Combs TP.
Brooks NL, et al. Among authors: perfetti mt.
Diabetes Obes Metab. 2007 May;9(3):246-58. doi: 10.1111/j.1463-1326.2006.00596.x.
Diabetes Obes Metab. 2007.
PMID: 17391150
Review.
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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Cui G, Botuyan MV, Drané P, Hu Q, Bragantini B, Thompson JR, Schuller DJ, Detappe A, Perfetti MT, James LI, Frye SV, Chowdhury D, Mer G.
Cui G, et al. Among authors: perfetti mt.
bioRxiv [Preprint]. 2023 Jul 18:2023.04.20.534960. doi: 10.1101/2023.04.20.534960.
bioRxiv. 2023.
PMID: 37131705
Free PMC article.
Updated.
Preprint.
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A method for the deprotection of alkylpinacolyl boronate esters.
Sun J, Perfetti MT, Santos WL.
Sun J, et al. Among authors: perfetti mt.
J Org Chem. 2011 May 6;76(9):3571-5. doi: 10.1021/jo200250y. Epub 2011 Apr 7.
J Org Chem. 2011.
PMID: 21449603
Free PMC article.
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