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Comparison of the GPVI inhibitors losartan and honokiol.
Onselaer MB, Nagy M, Pallini C, Pike JA, Perrella G, Quintanilla LG, Eble JA, Poulter NS, Heemskerk JWM, Watson SP. Onselaer MB, et al. Among authors: perrella g. Platelets. 2020;31(2):187-197. doi: 10.1080/09537104.2019.1585526. Epub 2019 Mar 8. Platelets. 2020. PMID: 30849265 Free PMC article.
Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?
Slater A, Perrella G, Onselaer MB, Martin EM, Gauer JS, Xu RG, Heemskerk JW, Ariëns RAS, Watson SP. Slater A, et al. Among authors: perrella g. Platelets. 2019;30(3):281-289. doi: 10.1080/09537104.2018.1508649. Epub 2018 Aug 15. Platelets. 2019. PMID: 30110193
Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation.
Perrella G, Huang J, Provenzale I, Swieringa F, Heubel-Moenen FCJI, Farndale RW, Roest M, van der Meijden PEJ, Thomas M, Ariëns RAS, Jandrot-Perrus M, Watson SP, Heemskerk JWM. Perrella G, et al. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):e97-e111. doi: 10.1161/ATVBAHA.120.314641. Epub 2020 Dec 3. Arterioscler Thromb Vasc Biol. 2021. PMID: 33267658 Free article.
Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear.
Perrella G, Montague SJ, Brown HC, Garcia Quintanilla L, Slater A, Stegner D, Thomas M, Heemskerk JWM, Watson SP. Perrella G, et al. Int J Mol Sci. 2022 Jan 1;23(1):493. doi: 10.3390/ijms23010493. Int J Mol Sci. 2022. PMID: 35008919 Free PMC article.
Protein C or Protein S deficiency associates with paradoxically impaired platelet-dependent thrombus and fibrin formation under flow.
Brouns SLN, Tullemans BME, Bulato C, Perrella G, Campello E, Spiezia L, van Geffen JP, Kuijpers MJE, van Oerle R, Spronk HMH, van der Meijden PEJ, Simioni P, Heemskerk JWM. Brouns SLN, et al. Among authors: perrella g. Res Pract Thromb Haemost. 2022 Mar 7;6(2):e12678. doi: 10.1002/rth2.12678. eCollection 2022 Feb. Res Pract Thromb Haemost. 2022. PMID: 35284776 Free PMC article.
S100A8/A9 drives the formation of procoagulant platelets through GPIbα.
Colicchia M, Schrottmaier WC, Perrella G, Reyat JS, Begum J, Slater A, Price J, Clark JC, Zhi Z, Simpson MJ, Bourne JH, Poulter NS, Khan AO, Nicolson PLR, Pugh M, Harrison P, Iqbal AJ, Rainger GE, Watson SP, Thomas MR, Mutch NJ, Assinger A, Rayes J. Colicchia M, et al. Among authors: perrella g. Blood. 2022 Dec 15;140(24):2626-2643. doi: 10.1182/blood.2021014966. Blood. 2022. PMID: 36026606 Free PMC article.
Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice.
Bourne JH, Perrella G, El-Awaisi J, Terry LV, Tinkova V, Hogg RL, Gant P, Grygielska B, Kalia N, Kavanagh D, Brill A, Dimitrov JD, Watson SP, Rayes J. Bourne JH, et al. Among authors: perrella g. J Thromb Haemost. 2024 Apr 24:S1538-7836(24)00226-5. doi: 10.1016/j.jtha.2024.04.008. Online ahead of print. J Thromb Haemost. 2024. PMID: 38670315 Free article.
65 results