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Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.
Walker CJ, Oaks JJ, Santhanam R, Neviani P, Harb JG, Ferenchak G, Ellis JJ, Landesman Y, Eisfeld AK, Gabrail NY, Smith CL, Caligiuri MA, Hokland P, Roy DC, Reid A, Milojkovic D, Goldman JM, Apperley J, Garzon R, Marcucci G, Shacham S, Kauffman MG, Perrotti D. Walker CJ, et al. Among authors: perrotti d. Blood. 2013 Oct 24;122(17):3034-44. doi: 10.1182/blood-2013-04-495374. Epub 2013 Aug 22. Blood. 2013. PMID: 23970380 Free PMC article.
BCR/ABL activates mdm2 mRNA translation via the La antigen.
Trotta R, Vignudelli T, Candini O, Intine RV, Pecorari L, Guerzoni C, Santilli G, Byrom MW, Goldoni S, Ford LP, Caligiuri MA, Maraia RJ, Perrotti D, Calabretta B. Trotta R, et al. Among authors: perrotti d. Cancer Cell. 2003 Feb;3(2):145-60. doi: 10.1016/s1535-6108(03)00020-5. Cancer Cell. 2003. PMID: 12620409 Free article.
Understanding the molecular basis of imatinib mesylate therapy in chronic myelogenous leukemia and the related mechanisms of resistance. Commentary re: A. N. Mohamed et al., The effect of imatinib mesylate on patients with Philadelphia chromosome-positive chronic myeloid leukemia with secondary chromosomal aberrations. Clin. Cancer Res., 9: 1333-1337, 2003.
Marcucci G, Perrotti D, Caligiuri MA. Marcucci G, et al. Among authors: perrotti d. Clin Cancer Res. 2003 Apr;9(4):1248-52. Clin Cancer Res. 2003. PMID: 12684391 Review. No abstract available.
The biology of CML blast crisis.
Calabretta B, Perrotti D. Calabretta B, et al. Among authors: perrotti d. Blood. 2004 Jun 1;103(11):4010-22. doi: 10.1182/blood-2003-12-4111. Epub 2004 Feb 24. Blood. 2004. PMID: 14982876 Free article. Review.
BCR/ABL, mRNA translation and apoptosis.
Perrotti D, Turturro F, Neviani P. Perrotti D, et al. Cell Death Differ. 2005 Jun;12(6):534-40. doi: 10.1038/sj.cdd.4401606. Cell Death Differ. 2005. PMID: 15846378 No abstract available.
134 results