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An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.
Zimmermannova O, Doktorova E, Stuchly J, Kanderova V, Kuzilkova D, Strnad H, Starkova J, Alberich-Jorda M, Falkenburg JHF, Trka J, Petrak J, Zuna J, Zaliova M. Zimmermannova O, et al. Among authors: petrak j. Oncogene. 2017 Oct 26;36(43):5985-5994. doi: 10.1038/onc.2017.210. Epub 2017 Jun 26. Oncogene. 2017. PMID: 28650474 Free PMC article.
Exosomes released by imatinib‑resistant K562 cells contain specific membrane markers, IFITM3, CD146 and CD36 and increase the survival of imatinib‑sensitive cells in the presence of imatinib.
Hrdinova T, Toman O, Dresler J, Klimentova J, Salovska B, Pajer P, Bartos O, Polivkova V, Linhartova J, Machova Polakova K, Kabickova H, Brodska B, Krijt M, Zivny J, Vyoral D, Petrak J. Hrdinova T, et al. Among authors: petrak j. Int J Oncol. 2021 Feb;58(2):238-250. doi: 10.3892/ijo.2020.5163. Epub 2020 Dec 23. Int J Oncol. 2021. PMID: 33491750
Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2.
Petrak J, Pospisilova J, Sedinova M, Jedelsky P, Lorkova L, Vit O, Kolar M, Strnad H, Benes J, Sedmera D, Cervenka L, Melenovsky V. Petrak J, et al. Proteome Sci. 2011 Nov 11;9(1):69. doi: 10.1186/1477-5956-9-69. Proteome Sci. 2011. PMID: 22078724 Free PMC article.
Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents.
Klanova M, Lorkova L, Vit O, Maswabi B, Molinsky J, Pospisilova J, Vockova P, Mavis C, Lateckova L, Kulvait V, Vejmelkova D, Jaksa R, Hernandez F, Trneny M, Vokurka M, Petrak J, Klener P Jr. Klanova M, et al. Among authors: petrak j. Mol Cancer. 2014 Jun 27;13:159. doi: 10.1186/1476-4598-13-159. Mol Cancer. 2014. PMID: 24972933 Free PMC article.
103 results