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Vamorolone, a dissociative steroidal compound, reduces collagen antibody-induced joint damage and inflammation when administered after disease onset.
Damsker JM, Cornish MR, Kanneboyina P, Kanneboyina I, Yu Q, Lipson R, Phadke A, Knoblach SM, Panchapakesan K, Morales M, Fiorillo AA, Partridge T, Nagaraju K. Damsker JM, et al. Among authors: phadke a. Inflamm Res. 2019 Nov;68(11):969-980. doi: 10.1007/s00011-019-01279-z. Epub 2019 Aug 24. Inflamm Res. 2019. PMID: 31446438 Free PMC article.
VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects.
Heier CR, Damsker JM, Yu Q, Dillingham BC, Huynh T, Van der Meulen JH, Sali A, Miller BK, Phadke A, Scheffer L, Quinn J, Tatem K, Jordan S, Dadgar S, Rodriguez OC, Albanese C, Calhoun M, Gordish-Dressman H, Jaiswal JK, Connor EM, McCall JM, Hoffman EP, Reeves EK, Nagaraju K. Heier CR, et al. Among authors: phadke a. EMBO Mol Med. 2013 Oct;5(10):1569-85. doi: 10.1002/emmm.201302621. Epub 2013 Sep 9. EMBO Mol Med. 2013. PMID: 24014378 Free PMC article.
Long-term treatment with naproxcinod significantly improves skeletal and cardiac disease phenotype in the mdx mouse model of dystrophy.
Uaesoontrachoon K, Quinn JL, Tatem KS, Van Der Meulen JH, Yu Q, Phadke A, Miller BK, Gordish-Dressman H, Ongini E, Miglietta D, Nagaraju K. Uaesoontrachoon K, et al. Among authors: phadke a. Hum Mol Genet. 2014 Jun 15;23(12):3239-49. doi: 10.1093/hmg/ddu033. Epub 2014 Jan 23. Hum Mol Genet. 2014. PMID: 24463621 Free PMC article.
Mitochondrial dysfunction and consequences in calpain-3-deficient muscle.
Jahnke VE, Peterson JM, Van Der Meulen JH, Boehler J, Uaesoontrachoon K, Johnston HK, Defour A, Phadke A, Yu Q, Jaiswal JK, Nagaraju K. Jahnke VE, et al. Among authors: phadke a. Skelet Muscle. 2020 Dec 11;10(1):37. doi: 10.1186/s13395-020-00254-1. Skelet Muscle. 2020. PMID: 33308300 Free PMC article.
Effects of Dantrolene Therapy on Disease Phenotype in Dystrophin Deficient mdx Mice.
Quinn JL, Huynh T, Uaesoontrachoon K, Tatem K, Phadke A, Van der Meulen JH, Yu Q, Nagaraju K. Quinn JL, et al. Among authors: phadke a. PLoS Curr. 2013 Nov 8;5:ecurrents.md.e246cf493a7edb1669f42fb735936b46. doi: 10.1371/currents.md.e246cf493a7edb1669f42fb735936b46. PLoS Curr. 2013. PMID: 24270550 Free PMC article.
197 results