Philpott A - Search Results

1

Palbociclib releases the latent differentiation capacity of neuroblastoma cells.

Ferguson KM, Gillen SL, Chaytor L, Poon E, Marcos D, Gomez RL, Woods LM, Mykhaylechko L, Elfari L, Martins da Costa B, Jamin Y, Carroll JS, Chesler L, Ali FR, Philpott A. Ferguson KM, et al. Among authors: philpott a. Dev Cell. 2023 Oct 9;58(19):1967-1982.e8. doi: 10.1016/j.devcel.2023.08.028. Epub 2023 Sep 20. Dev Cell. 2023. PMID: 37734383 Free article.

2

Super-enhancer associated core regulatory circuits mediate susceptibility to retinoic acid in neuroblastoma cells.

Gomez RL, Woods LM, Ramachandran R, Abou Tayoun AN, Philpott A, Ali FR. Gomez RL, et al. Among authors: philpott a. Front Cell Dev Biol. 2022 Sep 6;10:943924. doi: 10.3389/fcell.2022.943924. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36147741 Free PMC article.

3

The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma.

Parkinson LM, Gillen SL, Woods LM, Chaytor L, Marcos D, Ali FR, Carroll JS, Philpott A. Parkinson LM, et al. Among authors: philpott a. Front Cell Dev Biol. 2022 Oct 3;10:942579. doi: 10.3389/fcell.2022.942579. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36263020 Free PMC article.

4

Cell cycle regulation of proliferation versus differentiation in the central nervous system.

Hardwick LJ, Ali FR, Azzarelli R, Philpott A. Hardwick LJ, et al. Among authors: philpott a. Cell Tissue Res. 2015 Jan;359(1):187-200. doi: 10.1007/s00441-014-1895-8. Epub 2014 May 25. Cell Tissue Res. 2015. PMID: 24859217 Free PMC article. Review.

5

Dephosphorylation of the Proneural Transcription Factor ASCL1 Re-Engages a Latent Post-Mitotic Differentiation Program in Neuroblastoma.

Ali FR, Marcos D, Chernukhin I, Woods LM, Parkinson LM, Wylie LA, Papkovskaia TD, Davies JD, Carroll JS, Philpott A. Ali FR, et al. Among authors: philpott a. Mol Cancer Res. 2020 Dec;18(12):1759-1766. doi: 10.1158/1541-7786.MCR-20-0693. Epub 2020 Oct 12. Mol Cancer Res. 2020. PMID: 33046535 Free PMC article.

6

Elevated ASCL1 activity creates de novo regulatory elements associated with neuronal differentiation.

Woods LM, Ali FR, Gomez R, Chernukhin I, Marcos D, Parkinson LM, Tayoun ANA, Carroll JS, Philpott A. Woods LM, et al. Among authors: philpott a. BMC Genomics. 2022 Apr 3;23(1):255. doi: 10.1186/s12864-022-08495-8. BMC Genomics. 2022. PMID: 35366798 Free PMC article.

7

Tumoral heterogeneity in neuroblastoma.

Gomez RL, Ibragimova S, Ramachandran R, Philpott A, Ali FR. Gomez RL, et al. Among authors: philpott a. Biochim Biophys Acta Rev Cancer. 2022 Nov;1877(6):188805. doi: 10.1016/j.bbcan.2022.188805. Epub 2022 Sep 24. Biochim Biophys Acta Rev Cancer. 2022. PMID: 36162542 Free article. Review.

8

Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Göttgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A. Azzarelli R, et al. Among authors: philpott a. Dev Cell. 2017 May 8;41(3):274-286.e5. doi: 10.1016/j.devcel.2017.04.004. Epub 2017 Apr 27. Dev Cell. 2017. PMID: 28457793 Free PMC article.

9

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.

Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A. Ali FR, et al. Among authors: philpott a. Development. 2014 Jun;141(11):2216-24. doi: 10.1242/dev.106377. Epub 2014 May 12. Development. 2014. PMID: 24821983

10

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.

Hindley C, Ali F, McDowell G, Cheng K, Jones A, Guillemot F, Philpott A. Hindley C, et al. Among authors: philpott a. Development. 2012 May;139(10):1718-23. doi: 10.1242/dev.077552. Epub 2012 Apr 4. Development. 2012. PMID: 22491944 Free PMC article.

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