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An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling.
Sala G, Traini S, D'Egidio M, Vianale G, Rossi C, Piccolo E, Lattanzio R, Piantelli M, Tinari N, Natali PG, Muraro R, Iacobelli S; Consorzio Interuniversitario Nazionale per la Bio-Oncologia. Sala G, et al. Among authors: piccolo e. Oncogene. 2012 Mar 8;31(10):1275-86. doi: 10.1038/onc.2011.322. Epub 2011 Aug 8. Oncogene. 2012. PMID: 21822299
90K (Mac-2 BP) and galectins in tumor progression and metastasis.
Grassadonia A, Tinari N, Iurisci I, Piccolo E, Cumashi A, Innominato P, D'Egidio M, Natoli C, Piantelli M, Iacobelli S. Grassadonia A, et al. Among authors: piccolo e. Glycoconj J. 2002;19(7-9):551-6. doi: 10.1023/B:GLYC.0000014085.00706.d4. Glycoconj J. 2002. PMID: 14758079 Review.
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis.
Piccolo E, Tinari N, Semeraro D, Traini S, Fichera I, Cumashi A, La Sorda R, Spinella F, Bagnato A, Lattanzio R, D'Egidio M, Di Risio A, Stampolidis P, Piantelli M, Natoli C, Ullrich A, Iacobelli S. Piccolo E, et al. J Mol Med (Berl). 2013 Jan;91(1):83-94. doi: 10.1007/s00109-012-0936-6. Epub 2012 Aug 5. J Mol Med (Berl). 2013. PMID: 22864925
Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis.
Rabinovich GA, Cumashi A, Bianco GA, Ciavardelli D, Iurisci I, D'Egidio M, Piccolo E, Tinari N, Nifantiev N, Iacobelli S. Rabinovich GA, et al. Among authors: piccolo e. Glycobiology. 2006 Mar;16(3):210-20. doi: 10.1093/glycob/cwj056. Epub 2005 Nov 10. Glycobiology. 2006. PMID: 16282605
216 results