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Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Fonseca EMB, Trivella DBB, Scorsato V, Dias MP, Bazzo NL, Mandapati KR, de Oliveira FL, Ferreira-Halder CV, Pilli RA, Miranda PCML, Aparicio R. Fonseca EMB, et al. Among authors: pilli ra. Bioorg Med Chem. 2015 Aug 1;23(15):4462-4471. doi: 10.1016/j.bmc.2015.06.017. Epub 2015 Jun 14. Bioorg Med Chem. 2015. PMID: 26117648
(-)-Tarchonanthuslactone: Design of New Analogues, Evaluation of their Antiproliferative Activity on Cancer Cell Lines, and Preliminary Mechanistic Studies.
Toneto Novaes LF, Martins Avila C, Pelizzaro-Rocha KJ, Vendramini-Costa DB, Pereira Dias M, Barbosa Trivella DB, Ernesto de Carvalho J, Ferreira-Halder CV, Pilli RA. Toneto Novaes LF, et al. Among authors: pilli ra. ChemMedChem. 2015 Oct;10(10):1687-99. doi: 10.1002/cmdc.201500246. Epub 2015 Aug 25. ChemMedChem. 2015. PMID: 26305900
69 results