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Crystal structure of the gamma-2 herpesvirus LANA DNA binding domain identifies charged surface residues which impact viral latency.
Correia B, Cerqueira SA, Beauchemin C, Pires de Miranda M, Li S, Ponnusamy R, Rodrigues L, Schneider TR, Carrondo MA, Kaye KM, Simas JP, McVey CE. Correia B, et al. Among authors: pires de miranda m. PLoS Pathog. 2013;9(10):e1003673. doi: 10.1371/journal.ppat.1003673. Epub 2013 Oct 17. PLoS Pathog. 2013. PMID: 24146618 Free PMC article.
KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA.
Ponnusamy R, Petoukhov MV, Correia B, Custodio TF, Juillard F, Tan M, Pires de Miranda M, Carrondo MA, Simas JP, Kaye KM, Svergun DI, McVey CE. Ponnusamy R, et al. Among authors: pires de miranda m. Nucleic Acids Res. 2015 Nov 16;43(20):10039-54. doi: 10.1093/nar/gkv987. Epub 2015 Sep 30. Nucleic Acids Res. 2015. PMID: 26424851 Free PMC article.
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules.
Mikutis S, Rebelo M, Yankova E, Gu M, Tang C, Coelho AR, Yang M, Hazemi ME, Pires de Miranda M, Eleftheriou M, Robertson M, Vassiliou GS, Adams DJ, Simas JP, Corzana F, Schneekloth JS Jr, Tzelepis K, Bernardes GJL. Mikutis S, et al. Among authors: pires de miranda m. ACS Cent Sci. 2023 Apr 26;9(5):892-904. doi: 10.1021/acscentsci.3c00015. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252343 Free PMC article.
11 results