Plückthun A - Search Results

1

Crystal structure of the α_1B-adrenergic receptor reveals molecular determinants of selective ligand recognition.

Deluigi M, Morstein L, Schuster M, Klenk C, Merklinger L, Cridge RR, de Zhang LA, Klipp A, Vacca S, Vaid TM, Mittl PRE, Egloff P, Eberle SA, Zerbe O, Chalmers DK, Scott DJ, Plückthun A. Deluigi M, et al. Among authors: pluckthun a. Nat Commun. 2022 Jan 19;13(1):382. doi: 10.1038/s41467-021-27911-3. Nat Commun. 2022. PMID: 35046410 Free PMC article.

2

Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex.

Tissot AC, Ciatto C, Mittl PR, Grütter MG, Plückthun A. Tissot AC, et al. Among authors: pluckthun a. J Mol Biol. 2000 Sep 29;302(4):873-85. doi: 10.1006/jmbi.2000.4501. J Mol Biol. 2000. PMID: 10993729

3

Stabilizing ionic interactions in a full-consensus ankyrin repeat protein.

Merz T, Wetzel SK, Firbank S, Plückthun A, Grütter MG, Mittl PR. Merz T, et al. Among authors: pluckthun a. J Mol Biol. 2008 Feb 8;376(1):232-40. doi: 10.1016/j.jmb.2007.11.047. Epub 2007 Nov 22. J Mol Biol. 2008. PMID: 18155045

4

Designed armadillo repeat proteins as general peptide-binding scaffolds: consensus design and computational optimization of the hydrophobic core.

Parmeggiani F, Pellarin R, Larsen AP, Varadamsetty G, Stumpp MT, Zerbe O, Caflisch A, Plückthun A. Parmeggiani F, et al. Among authors: pluckthun a. J Mol Biol. 2008 Mar 7;376(5):1282-304. doi: 10.1016/j.jmb.2007.12.014. Epub 2007 Dec 14. J Mol Biol. 2008. PMID: 18222472 Free article.

5

Residue-resolved stability of full-consensus ankyrin repeat proteins probed by NMR.

Wetzel SK, Ewald C, Settanni G, Jurt S, Plückthun A, Zerbe O. Wetzel SK, et al. Among authors: pluckthun a. J Mol Biol. 2010 Sep 10;402(1):241-58. doi: 10.1016/j.jmb.2010.07.031. Epub 2010 Jul 21. J Mol Biol. 2010. PMID: 20654623

6

Structural determinants for improved stability of designed ankyrin repeat proteins with a redesigned C-capping module.

Kramer MA, Wetzel SK, Plückthun A, Mittl PR, Grütter MG. Kramer MA, et al. Among authors: pluckthun a. J Mol Biol. 2010 Dec 3;404(3):381-91. doi: 10.1016/j.jmb.2010.09.023. Epub 2010 Sep 17. J Mol Biol. 2010. PMID: 20851127

7

Structure-based optimization of designed Armadillo-repeat proteins.

Madhurantakam C, Varadamsetty G, Grütter MG, Plückthun A, Mittl PR. Madhurantakam C, et al. Among authors: pluckthun a. Protein Sci. 2012 Jul;21(7):1015-28. doi: 10.1002/pro.2085. Epub 2012 May 24. Protein Sci. 2012. PMID: 22544642 Free PMC article.

8

Optimization of designed armadillo repeat proteins by molecular dynamics simulations and NMR spectroscopy.

Alfarano P, Varadamsetty G, Ewald C, Parmeggiani F, Pellarin R, Zerbe O, Plückthun A, Caflisch A. Alfarano P, et al. Among authors: pluckthun a. Protein Sci. 2012 Sep;21(9):1298-314. doi: 10.1002/pro.2117. Protein Sci. 2012. PMID: 22767482 Free PMC article.

9

Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries.

Kummer L, Parizek P, Rube P, Millgramm B, Prinz A, Mittl PR, Kaufholz M, Zimmermann B, Herberg FW, Plückthun A. Kummer L, et al. Among authors: pluckthun a. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):E2248-57. doi: 10.1073/pnas.1205399109. Epub 2012 Jul 27. Proc Natl Acad Sci U S A. 2012. PMID: 22843676 Free PMC article.

10

Direct identification of ligand-receptor interactions on living cells and tissues.

Frei AP, Jeon OY, Kilcher S, Moest H, Henning LM, Jost C, Plückthun A, Mercer J, Aebersold R, Carreira EM, Wollscheid B. Frei AP, et al. Among authors: pluckthun a. Nat Biotechnol. 2012 Oct;30(10):997-1001. doi: 10.1038/nbt.2354. Epub 2012 Sep 16. Nat Biotechnol. 2012. PMID: 22983091

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