Plummer G - Search Results

1

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.

Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE. Ferdaoussi M, et al. Among authors: plummer g. J Clin Invest. 2015 Oct 1;125(10):3847-60. doi: 10.1172/JCI82498. Epub 2015 Sep 21. J Clin Invest. 2015. PMID: 26389676 Free PMC article.

2

SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets.

Hajmrle C, Ferdaoussi M, Plummer G, Spigelman AF, Lai K, Manning Fox JE, MacDonald PE. Hajmrle C, et al. Among authors: plummer g. Am J Physiol Endocrinol Metab. 2014 Oct 15;307(8):E664-73. doi: 10.1152/ajpendo.00168.2014. Epub 2014 Aug 19. Am J Physiol Endocrinol Metab. 2014. PMID: 25139051 Free PMC article.

3

Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction.

Fu J, Dai X, Plummer G, Suzuki K, Bautista A, Githaka JM, Senior L, Jensen M, Greitzer-Antes D, Manning Fox JE, Gaisano HY, Newgard CB, Touret N, MacDonald PE. Fu J, et al. Among authors: plummer g. Diabetes. 2017 Jul;66(7):1890-1900. doi: 10.2337/db16-1170. Epub 2017 Jun 12. Diabetes. 2017. PMID: 28607108 Free PMC article.

4

SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.

Dai XQ, Plummer G, Casimir M, Kang Y, Hajmrle C, Gaisano HY, Manning Fox JE, MacDonald PE. Dai XQ, et al. Among authors: plummer g. Diabetes. 2011 Mar;60(3):838-47. doi: 10.2337/db10-0440. Epub 2011 Jan 24. Diabetes. 2011. PMID: 21266332 Free PMC article.

5

SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells.

Ferdaoussi M, Fu J, Dai X, Manning Fox JE, Suzuki K, Smith N, Plummer G, MacDonald PE. Ferdaoussi M, et al. Among authors: plummer g. Sci Rep. 2017 Mar 21;7(1):248. doi: 10.1038/s41598-017-00344-z. Sci Rep. 2017. PMID: 28325894 Free PMC article.

6

Distinct and opposing roles for the phosphatidylinositol 3-OH kinase catalytic subunits p110α and p110β in the regulation of insulin secretion from rodent and human beta cells.

Kolic J, Spigelman AF, Plummer G, Leung E, Hajmrle C, Kin T, Shapiro AM, Manning Fox JE, MacDonald PE. Kolic J, et al. Among authors: plummer g. Diabetologia. 2013 Jun;56(6):1339-49. doi: 10.1007/s00125-013-2882-4. Epub 2013 Apr 9. Diabetologia. 2013. PMID: 23568272

7

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.

Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE. Dai XQ, et al. Among authors: plummer g. Diabetologia. 2012 Jun;55(6):1709-20. doi: 10.1007/s00125-012-2512-6. Epub 2012 Mar 13. Diabetologia. 2012. PMID: 22411134

8

A glucose-dependent spatial patterning of exocytosis in human β-cells is disrupted in type 2 diabetes.

Fu J, Githaka JM, Dai X, Plummer G, Suzuki K, Spigelman AF, Bautista A, Kim R, Greitzer-Antes D, Fox JEM, Gaisano HY, MacDonald PE. Fu J, et al. Among authors: plummer g. JCI Insight. 2019 May 14;5(12):e127896. doi: 10.1172/jci.insight.127896. JCI Insight. 2019. PMID: 31085831 Free PMC article.

9

DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals.

Vergari E, Plummer G, Dai X, MacDonald PE. Vergari E, et al. Among authors: plummer g. Biomolecules. 2012 May 24;2(2):269-81. doi: 10.3390/biom2020269. Biomolecules. 2012. PMID: 24970137 Free PMC article.

10

Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events.

Vilas GL, Corvi MM, Plummer GJ, Seime AM, Lambkin GR, Berthiaume LG. Vilas GL, et al. Among authors: plummer gj. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6542-7. doi: 10.1073/pnas.0600824103. Epub 2006 Apr 14. Proc Natl Acad Sci U S A. 2006. PMID: 16617111 Free PMC article.

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