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Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing.
Jo S, Das S, Williams A, Chretien AS, Pagliardini T, Le Roy A, Fernandez JP, Le Clerre D, Jahangiri B, Chion-Sotinel I, Rozlan S, Dessez E, Gouble A, Dusséaux M, Galetto R, Duclert A, Marcenaro E, Devillier R, Olive D, Duchateau P, Poirot L, Valton J. Jo S, et al. Among authors: poirot l. Nat Commun. 2022 Jun 30;13(1):3453. doi: 10.1038/s41467-022-30896-2. Nat Commun. 2022. PMID: 35773273 Free PMC article.
Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.
Daboussi F, Zaslavskiy M, Poirot L, Loperfido M, Gouble A, Guyot V, Leduc S, Galetto R, Grizot S, Oficjalska D, Perez C, Delacôte F, Dupuy A, Chion-Sotinel I, Le Clerre D, Lebuhotel C, Danos O, Lemaire F, Oussedik K, Cédrone F, Epinat JC, Smith J, Yáñez-Muñoz RJ, Dickson G, Popplewell L, Koo T, VandenDriessche T, Chuah MK, Duclert A, Duchateau P, Pâques F. Daboussi F, et al. Among authors: poirot l. Nucleic Acids Res. 2012 Jul;40(13):6367-79. doi: 10.1093/nar/gks268. Epub 2012 Mar 29. Nucleic Acids Res. 2012. PMID: 22467209 Free PMC article.
Optimized tuning of TALEN specificity using non-conventional RVDs.
Juillerat A, Pessereau C, Dubois G, Guyot V, Maréchal A, Valton J, Daboussi F, Poirot L, Duclert A, Duchateau P. Juillerat A, et al. Among authors: poirot l. Sci Rep. 2015 Jan 30;5:8150. doi: 10.1038/srep08150. Sci Rep. 2015. PMID: 25632877 Free PMC article.
Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies.
Poirot L, Philip B, Schiffer-Mannioui C, Le Clerre D, Chion-Sotinel I, Derniame S, Potrel P, Bas C, Lemaire L, Galetto R, Lebuhotel C, Eyquem J, Cheung GW, Duclert A, Gouble A, Arnould S, Peggs K, Pule M, Scharenberg AM, Smith J. Poirot L, et al. Cancer Res. 2015 Sep 15;75(18):3853-64. doi: 10.1158/0008-5472.CAN-14-3321. Epub 2015 Jul 16. Cancer Res. 2015. PMID: 26183927
36 results