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Page 1
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.
Yuan S, Yin X, Meng X, Chan JF, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan CC, Poon VK, Lee AC, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Lau CY, Sit KY, Au WK, Wang R, Zhang YY, Tang YD, Clausen TM, Pihl J, Oh J, Sze KH, Zhang AJ, Chu H, Kok KH, Wang D, Cai XH, Esko JD, Hung IF, Li RA, Chen H, Sun H, Jin DY, Sun R, Chanda SK, Yuen KY. Yuan S, et al. Among authors: lai pm. Nature. 2021 May;593(7859):418-423. doi: 10.1038/s41586-021-03431-4. Epub 2021 Mar 16. Nature. 2021. PMID: 33727703
SaeR as a novel target for antivirulence therapy against Staphylococcus aureus.
Gao P, Wei Y, Hou S, Lai PM, Liu H, Tai SSC, Tang VYM, Prakash PH, Sze KH, Chen JHK, Sun H, Li X, Kao RY. Gao P, et al. Among authors: lai pm. Emerg Microbes Infect. 2023 Dec;12(2):2254415. doi: 10.1080/22221751.2023.2254415. Emerg Microbes Infect. 2023. PMID: 37671453 Free PMC article.
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.
Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Yuan S, et al. Among authors: lai pm. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. Nat Commun. 2019. PMID: 30631056 Free PMC article.
Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway.
Yan B, Yuan S, Cao J, Fung K, Lai PM, Yin F, Sze KH, Qin Z, Xie Y, Ye ZW, Yuen TT, Chik KK, Tsang JO, Zou Z, Chan CC, Luo C, Cai JP, Chan KH, Chung TW, Tam AR, Chu H, Jin DY, Hung IF, Yuen KY, Kao RY, Chan JF. Yan B, et al. Among authors: lai pm. Int J Biol Sci. 2022 Jul 11;18(12):4744-4755. doi: 10.7150/ijbs.73057. eCollection 2022. Int J Biol Sci. 2022. PMID: 35874954 Free PMC article.
13 results