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β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.
Hilpert H, Guba W, Woltering TJ, Wostl W, Pinard E, Mauser H, Mayweg AV, Rogers-Evans M, Humm R, Krummenacher D, Muser T, Schnider C, Jacobsen H, Ozmen L, Bergadano A, Banner DW, Hochstrasser R, Kuglstatter A, David-Pierson P, Fischer H, Polara A, Narquizian R. Hilpert H, et al. Among authors: polara a. J Med Chem. 2013 May 23;56(10):3980-95. doi: 10.1021/jm400225m. Epub 2013 May 2. J Med Chem. 2013. PMID: 23590342
A fascination with 1,2-diacetals.
Ley SV, Polara A. Ley SV, et al. Among authors: polara a. J Org Chem. 2007 Aug 3;72(16):5943-59. doi: 10.1021/jo0703451. Epub 2007 Apr 13. J Org Chem. 2007. PMID: 17430000
Targeting C-reactive protein for the treatment of cardiovascular disease.
Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, Gray GA, Sabin CA, Jenvey MC, Kolstoe SE, Thompson D, Wood SP. Pepys MB, et al. Among authors: polara a. Nature. 2006 Apr 27;440(7088):1217-21. doi: 10.1038/nature04672. Nature. 2006. PMID: 16642000
RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta-site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain.
Honer M, Polara A, Kuwabara H, Jacobsen H, Pähler A, Hartung T, Caruso A, Esterhazy D, Stoffel M, Dannals RF, Wong DF, Borroni E, Gobbi LC. Honer M, et al. Among authors: polara a. J Labelled Comp Radiopharm. 2023 Jul;66(9):222-236. doi: 10.1002/jlcr.4025. Epub 2023 May 11. J Labelled Comp Radiopharm. 2023. PMID: 37095603
Mapping European Association of Urology Guideline Practice Across Europe: An Audit of Androgen Deprivation Therapy Use Before Prostate Cancer Surgery in 6598 Cases in 187 Hospitals Across 31 European Countries.
MacLennan S, Azevedo N, Duncan E, Dunsmore J, Fullwood L, Lumen N, Plass K, Ribal MJ, Roobol MJ, Nieboer D, Schouten N, Skolarus TA, Smith EJ, N'Dow J, Mottet N, Briganti A; Pan-European National Urological Society IMAGINE Collaborative (see Supplemental material for group members affiliations):. MacLennan S, et al. Eur Urol. 2023 May;83(5):393-401. doi: 10.1016/j.eururo.2022.12.031. Epub 2023 Jan 11. Eur Urol. 2023. PMID: 36639296 Free article.
Conservative management of primary malignant melanoma of the bladder: a case report.
Rapisarda S, Bada M, Polara A, Crocetto F, Creta M, Chiancone F, Occhipinti M, Bertoloni R, Marciano A, Aresu L, Nazaraj A, Grosso S, Grosso G. Rapisarda S, et al. Among authors: polara a. J Med Case Rep. 2021 Feb 5;15(1):39. doi: 10.1186/s13256-020-02602-7. J Med Case Rep. 2021. PMID: 33541425 Free PMC article.
The role of multiparametric resonance and biopsy in prostate cancer detection: comparison with definitive histological report after laparoscopic/robotic radical prostatectomy.
Rapisarda S, Bada M, Crocetto F, Barone B, Arcaniolo D, Polara A, Imbimbo C, Grosso G. Rapisarda S, et al. Among authors: polara a. Abdom Radiol (NY). 2020 Dec;45(12):4178-4184. doi: 10.1007/s00261-020-02798-8. Epub 2020 Oct 13. Abdom Radiol (NY). 2020. PMID: 33048224 Free PMC article.
Transperitoneal vs retroperitoneal minimally invasive partial nephrectomy: comparison of perioperative outcomes and functional follow-up in a large multi-institutional cohort (The RECORD 2 Project).
Porpiglia F, Mari A, Amparore D, Fiori C, Antonelli A, Artibani W, Bove P, Brunocilla E, Capitanio U, Da Pozzo L, Di Maida F, Gontero P, Longo N, Marra G, Rocco B, Schiavina R, Simeone C, Siracusano S, Tellini R, Terrone C, Villari D, Ficarra V, Carini M, Minervini A; RECORD 2 Project. Porpiglia F, et al. Surg Endosc. 2021 Aug;35(8):4295-4304. doi: 10.1007/s00464-020-07919-4. Epub 2020 Aug 27. Surg Endosc. 2021. PMID: 32856156 Free PMC article.
15 results