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Contribution of several metabolites of the vitamin D analog 20-epi-22-oxa-24a,26a,27a-tri-homo-1,25-(OH)(2) vitamin D(3) (KH 1060) to the overall biological activity of KH1060 by a shared mechanism of action.
van den Bemd GC, Dilworth FJ, Makin HL, Prahl JM, Deluca HF, Jones G, Pols HA, van Leeuwen JP. van den Bemd GC, et al. Among authors: pols ha. Biochem Pharmacol. 2000 Mar 15;59(6):621-7. doi: 10.1016/s0006-2952(99)00371-8. Biochem Pharmacol. 2000. PMID: 10677578
A central dinucleotide within vitamin D response elements modulates DNA binding and transactivation by the vitamin D receptor in cellular response to natural and synthetic ligands.
van den Bemd GJ, Jhamai M, Staal A, van Wijnen AJ, Lian JB, Stein GS, Pols HA, van Leeuwen JP. van den Bemd GJ, et al. Among authors: pols ha. J Biol Chem. 2002 Apr 26;277(17):14539-46. doi: 10.1074/jbc.M111224200. Epub 2002 Feb 7. J Biol Chem. 2002. PMID: 11834737 Free article.
383 results