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NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Biebl MM, Delhommel F, Faust O, Zak KM, Agam G, Guo X, Mühlhofer M, Dahiya V, Hillebrand D, Popowicz GM, Kampmann M, Lamb DC, Rosenzweig R, Sattler M, Buchner J. Biebl MM, et al. Among authors: popowicz gm. Mol Cell. 2022 Feb 3;82(3):555-569.e7. doi: 10.1016/j.molcel.2021.12.031. Epub 2022 Jan 20. Mol Cell. 2022. PMID: 35063133 Free article.
Identification of small-molecule inhibitors of USP2a.
Tomala MD, Magiera-Mularz K, Kubica K, Krzanik S, Zieba B, Musielak B, Pustula M, Popowicz GM, Sattler M, Dubin G, Skalniak L, Holak TA. Tomala MD, et al. Among authors: popowicz gm. Eur J Med Chem. 2018 Apr 25;150:261-267. doi: 10.1016/j.ejmech.2018.03.009. Epub 2018 Mar 5. Eur J Med Chem. 2018. PMID: 29529503
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K. Brenke JK, et al. Among authors: popowicz gm. J Biol Chem. 2018 Aug 24;293(34):13191-13203. doi: 10.1074/jbc.RA118.002649. Epub 2018 Jun 27. J Biol Chem. 2018. PMID: 29950522 Free PMC article.
105 results