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Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies.
DiJoseph JF, Armellino DC, Boghaert ER, Khandke K, Dougher MM, Sridharan L, Kunz A, Hamann PR, Gorovits B, Udata C, Moran JK, Popplewell AG, Stephens S, Frost P, Damle NK. DiJoseph JF, et al. Among authors: popplewell ag. Blood. 2004 Mar 1;103(5):1807-14. doi: 10.1182/blood-2003-07-2466. Epub 2003 Nov 13. Blood. 2004. PMID: 14615373 Free article.
Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22.
DiJoseph JF, Popplewell A, Tickle S, Ladyman H, Lawson A, Kunz A, Khandke K, Armellino DC, Boghaert ER, Hamann P, Zinkewich-Peotti K, Stephens S, Weir N, Damle NK. DiJoseph JF, et al. Cancer Immunol Immunother. 2005 Jan;54(1):11-24. doi: 10.1007/s00262-004-0572-2. Cancer Immunol Immunother. 2005. PMID: 15693135 Free PMC article.
In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes.
Berry LM, Adams R, Airey M, Bracher MG, Bourne T, Carrington B, Cross AS, Davies GC, Finney HM, Foulkes R, Gozzard N, Griffin RA, Hailu H, Lamour SD, Lawson AD, Lightwood DJ, McKnight AJ, O'Dowd VL, Oxbrow AK, Popplewell AG, Shaw S, Stephens PE, Sweeney B, Tomlinson KL, Uhe C, Palframan RT. Berry LM, et al. Among authors: popplewell ag. Int Immunopharmacol. 2009 Feb;9(2):201-6. doi: 10.1016/j.intimp.2008.11.001. Epub 2008 Nov 27. Int Immunopharmacol. 2009. PMID: 19041426
An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Schepens B, van Schie L, Nerinckx W, Roose K, Van Breedam W, Fijalkowska D, Devos S, Weyts W, De Cae S, Vanmarcke S, Lonigro C, Eeckhaut H, Van Herpe D, Borloo J, Oliveira AF, Catani JPP, Creytens S, De Vlieger D, Michielsen G, Marchan JCZ, Moschonas GD, Rossey I, Sedeyn K, Van Hecke A, Zhang X, Langendries L, Jacobs S, Ter Horst S, Seldeslachts L, Liesenborghs L, Boudewijns R, Thibaut HJ, Dallmeier K, Velde GV, Weynand B, Beer J, Schnepf D, Ohnemus A, Remory I, Foo CS, Abdelnabi R, Maes P, Kaptein SJF, Rocha-Pereira J, Jochmans D, Delang L, Peelman F, Staeheli P, Schwemmle M, Devoogdt N, Tersago D, Germani M, Heads J, Henry A, Popplewell A, Ellis M, Brady K, Turner A, Dombrecht B, Stortelers C, Neyts J, Callewaert N, Saelens X. Schepens B, et al. Sci Transl Med. 2021 Nov 24;13(621):eabi7826. doi: 10.1126/scitranslmed.abi7826. Epub 2021 Nov 24. Sci Transl Med. 2021. PMID: 34609205 Free PMC article.
Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans.
Rijal P, Elias SC, Machado SR, Xiao J, Schimanski L, O'Dowd V, Baker T, Barry E, Mendelsohn SC, Cherry CJ, Jin J, Labbé GM, Donnellan FR, Rampling T, Dowall S, Rayner E, Findlay-Wilson S, Carroll M, Guo J, Xu XN, Huang KA, Takada A, Burgess G, McMillan D, Popplewell A, Lightwood DJ, Draper SJ, Townsend AR. Rijal P, et al. Cell Rep. 2019 Apr 2;27(1):172-186.e7. doi: 10.1016/j.celrep.2019.03.020. Cell Rep. 2019. PMID: 30943399 Free article. Clinical Trial.
28 results