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Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.
Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I. Paul F, et al. Among authors: porse bt. Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Cell. 2015. PMID: 26627738 Free article.
Initiation of MLL-rearranged AML is dependent on C/EBPα.
Ohlsson E, Hasemann MS, Willer A, Lauridsen FK, Rapin N, Jendholm J, Porse BT. Ohlsson E, et al. Among authors: porse bt. J Exp Med. 2014 Jan 13;211(1):5-13. doi: 10.1084/jem.20130932. Epub 2013 Dec 23. J Exp Med. 2014. PMID: 24367003 Free PMC article.
C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors.
Hasemann MS, Lauridsen FK, Waage J, Jakobsen JS, Frank AK, Schuster MB, Rapin N, Bagger FO, Hoppe PS, Schroeder T, Porse BT. Hasemann MS, et al. Among authors: porse bt. PLoS Genet. 2014 Jan;10(1):e1004079. doi: 10.1371/journal.pgen.1004079. Epub 2014 Jan 9. PLoS Genet. 2014. PMID: 24415956 Free PMC article.
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
Willer A, Jakobsen JS, Ohlsson E, Rapin N, Waage J, Billing M, Bullinger L, Karlsson S, Porse BT. Willer A, et al. Among authors: porse bt. Leukemia. 2015 May;29(5):1018-31. doi: 10.1038/leu.2014.307. Epub 2014 Oct 28. Leukemia. 2015. PMID: 25349154
120 results