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Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor.
Kung DW, Coffey SB, Jones RM, Cabral S, Jiao W, Fichtner M, Carpino PA, Rose CR, Hank RF, Lopaze MG, Swartz R, Chen HT, Hendsch Z, Posner B, Wielis CF, Manning B, Dubins J, Stock IA, Varma S, Campbell M, DeBartola D, Kosa-Maines R, Steyn SJ, McClure KF. Kung DW, et al. Among authors: posner b. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4281-7. doi: 10.1016/j.bmcl.2012.05.024. Epub 2012 May 17. Bioorg Med Chem Lett. 2012. PMID: 22677316
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum.
Lawong A, Gahalawat S, Okombo J, Striepen J, Yeo T, Mok S, Deni I, Bridgford JL, Niederstrasser H, Zhou A, Posner B, Wittlin S, Gamo FJ, Crespo B, Churchyard A, Baum J, Mittal N, Winzeler E, Laleu B, Palmer MJ, Charman SA, Fidock DA, Ready JM, Phillips MA. Lawong A, et al. Among authors: posner b. J Med Chem. 2021 Mar 11;64(5):2739-2761. doi: 10.1021/acs.jmedchem.0c02022. Epub 2021 Feb 23. J Med Chem. 2021. PMID: 33620219 Free PMC article.
Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening.
Piala AT, Akella R, Potts MB, Dudics-Giagnocavo SA, He H, Wei S, White MA, Posner BA, Goldsmith EJ. Piala AT, et al. Among authors: posner ba. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3923-7. doi: 10.1016/j.bmcl.2016.07.016. Epub 2016 Jul 6. Bioorg Med Chem Lett. 2016. PMID: 27426302
Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein.
White K, Esparza M, Liang J, Bhat P, Naidoo J, McGovern BL, Williams MAP, Alabi BR, Shay J, Niederstrasser H, Posner B, García-Sastre A, Ready J, Fontoura BMA. White K, et al. Among authors: posner b. J Med Chem. 2021 Aug 12;64(15):10951-10966. doi: 10.1021/acs.jmedchem.1c00304. Epub 2021 Jul 14. J Med Chem. 2021. PMID: 34260245 Free PMC article.
Tumor-Activated Benzothiazole Inhibitors of Stearoyl-CoA Desaturase.
Williams NS, Gonzales S, Naidoo J, Rivera-Cancel G, Voruganti S, Mallipeddi P, Theodoropoulos PC, Geboers S, Chen H, Ortiz F, Posner B, Nijhawan D, Ready JM. Williams NS, et al. Among authors: posner b. J Med Chem. 2020 Sep 10;63(17):9773-9786. doi: 10.1021/acs.jmedchem.0c00899. Epub 2020 Aug 19. J Med Chem. 2020. PMID: 32787093
374 results