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Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages.
Nature. 2017 Mar 16;543(7645):428-432. doi: 10.1038/nature21409. Epub 2017 Mar 8.
Nature. 2017.
PMID: 28273064
Free PMC article.
Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells.
Pourzia AL, Olson ML, Bailey SR, Boroughs AC, Aryal A, Ryan J, Maus MV, Letai A.
Pourzia AL, et al.
Cell Death Dis. 2023 Apr 13;14(4):267. doi: 10.1038/s41419-023-05727-x.
Cell Death Dis. 2023.
PMID: 37055388
Free PMC article.
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De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients.
Akhavan D, Pourzia AL, Nourian AA, Williams KJ, Nathanson D, Babic I, Villa GR, Tanaka K, Nael A, Yang H, Dang J, Vinters HV, Yong WH, Flagg M, Tamanoi F, Sasayama T, James CD, Kornblum HI, Cloughesy TF, Cavenee WK, Bensinger SJ, Mischel PS.
Akhavan D, et al. Among authors: pourzia al.
Cancer Discov. 2013 May;3(5):534-47. doi: 10.1158/2159-8290.CD-12-0502. Epub 2013 Mar 26.
Cancer Discov. 2013.
PMID: 23533263
Free PMC article.
Clinical Trial.
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An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.
Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ.
Williams KJ, et al. Among authors: pourzia al.
Cancer Res. 2013 May 1;73(9):2850-62. doi: 10.1158/0008-5472.CAN-13-0382-T. Epub 2013 Feb 25.
Cancer Res. 2013.
PMID: 23440422
Free PMC article.
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