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Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.
Bedogni B, O'Neill MS, Welford SM, Bouley DM, Giaccia AJ, Denko NC, Powell MB. Bedogni B, et al. Among authors: powell mb. Cancer Res. 2004 Apr 1;64(7):2552-60. doi: 10.1158/0008-5472.can-03-3327. Cancer Res. 2004. PMID: 15059911
Notch1 is an effector of Akt and hypoxia in melanoma development.
Bedogni B, Warneke JA, Nickoloff BJ, Giaccia AJ, Powell MB. Bedogni B, et al. Among authors: powell mb. J Clin Invest. 2008 Nov;118(11):3660-70. doi: 10.1172/JCI36157. Epub 2008 Oct 16. J Clin Invest. 2008. PMID: 18924608 Free PMC article.
Unique transforming properties of Notch1 in human melanocytes.
Bedogni B, Powell MB. Bedogni B, et al. Among authors: powell mb. Pigment Cell Melanoma Res. 2009 Dec;22(6):702-3. doi: 10.1111/j.1755-148X.2009.00625.x. Epub 2009 Aug 26. Pigment Cell Melanoma Res. 2009. PMID: 19708913 No abstract available.
CTGF is a therapeutic target for metastatic melanoma.
Finger EC, Cheng CF, Williams TR, Rankin EB, Bedogni B, Tachiki L, Spong S, Giaccia AJ, Powell MB. Finger EC, et al. Among authors: powell mb. Oncogene. 2014 Feb 27;33(9):1093-100. doi: 10.1038/onc.2013.47. Epub 2013 Feb 25. Oncogene. 2014. PMID: 23435419 Free PMC article.
Effects of perillyl alcohol on melanoma in the TPras mouse model.
Lluria-Prevatt M, Morreale J, Gregus J, Alberts DS, Kaper F, Giaccia A, Powell MB. Lluria-Prevatt M, et al. Among authors: powell mb. Cancer Epidemiol Biomarkers Prev. 2002 Jun;11(6):573-9. Cancer Epidemiol Biomarkers Prev. 2002. PMID: 12050099
111 results